SCHEMBL21454061

SCHEMBL21454061

c1ccc2c(c1)sc1c2ccc2c3cccc4c5ccccc5c5cccc6sc7cccc(c7c65)n(c43)c21

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.39
MAPT P10636 2/20 0.34
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
ALOX5 P09917 1/20 0.33
PARP14 Q460N5 1/20 0.32
TNKS O95271 1/20 0.30
TNKS2 Q9H2K2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21454079 0.93 GPR3 (0.40) GPR3MAPTALDH1A1HPGDRAB9A
SCHEMBL21454133 0.89 GPR3 (0.37) GPR3MAPTALDH1A1HPGDRAB9A
SCHEMBL21453523 0.89 GPR3 (0.37) GPR3MAPTALDH1A1HPGDRAB9A
SCHEMBL21453477 0.87 GPR3 (0.41) GPR3MAPTALDH1A1HPGDRAB9A
SCHEMBL21454062 0.86 GPR3 (0.37) GPR3MAPTALDH1A1HPGDRAB9A
SCHEMBL19890696 0.85 GPR3 (0.42) GPR3MAPTALDH1A1HPGDRAB9A
SCHEMBL21453644 0.84 GPR3 (0.37) GPR3MAPTALDH1A1HPGDRAB9A
SCHEMBL19563760 0.82 GPR3 (0.48) GPR3MAPTALDH1A1HPGDRAB9A
SCHEMBL21454134 0.80 GPR3 (0.37) GPR3MAPTALDH1A1HPGDRAB9A
SCHEMBL21454057 0.80 GPR3 (0.38) GPR3MAPTALDH1A1HPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11038121-B2 9 membered ring carbazole compounds Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-06-15 US disclosed
US-20190312214-A1 9 MEMBERED RING CARBAZOLE COMPOUNDS BEIJING SUMMER SPROUT TECHNOLOGY CO., LTD (CN) 2019-10-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11038121-B2 9 membered ring carbazole compounds SLC25A21, OCIAD2, OXA1L GPR3 478/4885MAPT 2041/4885ALDH1A1 802/4885
US-20190312214-A1 9 MEMBERED RING CARBAZOLE COMPOUNDS SLC25A21, OCIAD2, OXA1L GPR3 478/4885MAPT 2041/4885ALDH1A1 802/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.