SCHEMBL21453479

SCHEMBL21453479

c1ccc(-c2cccc(-c3nc(-c4ccccc4)nc(-c4ccc5c(c4)c4cccc6c7ccccc7c7ccccc7c7ccccc7n5c64)n3)c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSPO P30536 2/20 0.38
NPY5R Q15761 2/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
ALDH1A1 P00352 2/20 0.36
MAPT P10636 2/20 0.36
HPGD P15428 2/20 0.36
KDM4E B2RXH2 2/20 0.35
ATM Q13315 1/20 0.35
LMNA P02545 1/20 0.35
GLA P06280 1/20 0.35
GP6 Q9HCN6 1/20 0.34
NR3C1 P04150 1/20 0.34
TSHR P16473 1/20 0.34
HSD17B10 Q99714 1/20 0.34
DNM1 Q05193 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21276397 0.99 TSPO (0.39) TSPONPY5RMEN1KMT2AALDH1A1
SCHEMBL21276430 0.99 TSPO (0.39) TSPONPY5RMEN1KMT2AALDH1A1
SCHEMBL21276422 0.99 TSPO (0.39) TSPONPY5RMEN1KMT2AALDH1A1
SCHEMBL21276431 0.99 TSPO (0.39) TSPONPY5RMEN1KMT2AALDH1A1
SCHEMBL21276434 0.99 TSPO (0.39) TSPONPY5RMEN1KMT2AALDH1A1
SCHEMBL21276398 0.99 TSPO (0.39) TSPONPY5RMEN1KMT2AALDH1A1
SCHEMBL21276396 0.99 TSPO (0.39) TSPONPY5RMEN1KMT2AALDH1A1
SCHEMBL21453583 0.99 NPY5R (0.37) TSPONPY5RMEN1KMT2AALDH1A1
SCHEMBL21276374 0.97 TSPO (0.40) TSPONPY5RMEN1KMT2AALDH1A1
SCHEMBL21453474 0.97 NPY5R (0.38) TSPONPY5RMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11038121-B2 9 membered ring carbazole compounds Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-06-15 US disclosed
US-20190312214-A1 9 MEMBERED RING CARBAZOLE COMPOUNDS BEIJING SUMMER SPROUT TECHNOLOGY CO., LTD (CN) 2019-10-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11038121-B2 9 membered ring carbazole compounds SLC25A21, OCIAD2, OXA1L TSPO 136/4885NPY5R 3583/4885MEN1 4538/4885
US-20190312214-A1 9 MEMBERED RING CARBAZOLE COMPOUNDS SLC25A21, OCIAD2, OXA1L TSPO 136/4885NPY5R 3583/4885MEN1 4538/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.