SCHEMBL21276397

SCHEMBL21276397

c1ccc(-c2ccc(-c3nc(-c4ccc(-c5ccccc5)cc4)nc(-c4cccc(-c5ccc6c(c5)c5cccc7c8ccccc8n6c75)c4)n3)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSPO P30536 1/20 0.39
NPY5R Q15761 1/20 0.37
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
ALDH1A1 P00352 3/20 0.36
MAPT P10636 3/20 0.36
HPGD P15428 3/20 0.36
KDM4E B2RXH2 3/20 0.35
ATM Q13315 1/20 0.35
LMNA P02545 1/20 0.35
GLA P06280 1/20 0.35
GP6 Q9HCN6 1/20 0.35
NR3C1 P04150 1/20 0.35
TSHR P16473 1/20 0.35
HSD17B10 Q99714 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
POLB P06746 1/20 0.34
HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21276398 1.00 TSPO (0.39) TSPONPY5RMEN1KMT2AALDH1A1
SCHEMBL21276431 1.00 TSPO (0.39) TSPONPY5RMEN1KMT2AALDH1A1
SCHEMBL21276434 1.00 TSPO (0.39) TSPONPY5RMEN1KMT2AALDH1A1
SCHEMBL21276422 1.00 TSPO (0.39) TSPONPY5RMEN1KMT2AALDH1A1
SCHEMBL21276396 1.00 TSPO (0.39) TSPONPY5RMEN1KMT2AALDH1A1
SCHEMBL21276430 1.00 TSPO (0.39) TSPONPY5RMEN1KMT2AALDH1A1
SCHEMBL21453479 0.99 TSPO (0.38) TSPONPY5RMEN1KMT2AALDH1A1
SCHEMBL21276374 0.99 TSPO (0.40) TSPONPY5RMEN1KMT2AALDH1A1
SCHEMBL21453583 0.97 NPY5R (0.37) TSPONPY5RMEN1KMT2AALDH1A1
SCHEMBL21453474 0.96 NPY5R (0.38) TSPONPY5RMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240032421-A1 Charge Transporting Material, Organic Electroluminescent Element, Light Emitting Device, Display Device And Illumination Device UDC IRELAND LIMITED (IE) 2024-01-25 US disclosed
US-20240032421-A1 Charge Transporting Material, Organic Electroluminescent Element, Light Emitting Device, Display Device And Illumination Device UDC IRELAND LIMITED (IE) 2024-01-25 US disclosed
US-11800798-B2 Charge transporting material, organic electroluminescent element, light emitting device, display device and illumination device UDC IRELAND LIMITED (IE) 2023-10-24 US disclosed
US-11800798-B2 Charge transporting material, organic electroluminescent element, light emitting device, display device and illumination device UDC IRELAND LIMITED (IE) 2023-10-24 US disclosed
US-20210249611-A1 Charge Transporting Material, Organic Electroluminescent Element, Light Emitting Device, Display Device And Illumination Device UDC IRELAND LTD (IE) 2021-08-12 US disclosed
US-11038122-B2 Charge transporting material, organic electroluminescent element, light emitting device, display device and illumination device UDC IRELAND LIMITED (IE) 2021-06-15 US disclosed
US-20190334098-A1 Charge Transporting Material, Organic Electroluminescent Element, Light Emitting Device, Display Device And Illumination Device UDC IRELAND LTD (IE) 2019-10-31 US disclosed
US-10388886-B2 Charge transporting material, organic electroluminescent element, light emitting device, display device and illumination device UDC IRELAND LIMITED (IE) 2019-08-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11038122-B2 Charge transporting material, organic electroluminescent element, light emitting device, display device and illumination device TMEM109, SLC39A11, SLC39A14 TSPO 264/4885NPY5R 4491/4885MEN1 1647/4885
US-20210249611-A1 Charge Transporting Material, Organic Electroluminescent Element, Light Emitting Device, Display Device And Illumination Device TMEM109, SLC39A11, SLC39A14 TSPO 264/4885NPY5R 4491/4885MEN1 1647/4885
US-11800798-B2 Charge transporting material, organic electroluminescent element, light emitting device, display device and illumination device TMEM109, SLC39A11, SLC39A14 TSPO 264/4885NPY5R 4491/4885MEN1 1647/4885
US-20240032421-A1 Charge Transporting Material, Organic Electroluminescent Element, Light Emitting Device, Display Device And Illumination Device TMEM109, SLC39A11, SLC39A14 TSPO 264/4885NPY5R 4491/4885MEN1 1647/4885
US-10388886-B2 Charge transporting material, organic electroluminescent element, light emitting device, display device and illumination device SLC39A11, TMEM109, SLC39A14 TSPO 238/4885NPY5R 4410/4885MEN1 1733/4885
US-20190334098-A1 Charge Transporting Material, Organic Electroluminescent Element, Light Emitting Device, Display Device And Illumination Device NR2E3, OR51E2, GNA11 TSPO 842/4885NPY5R 2696/4885MEN1 2635/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.