SCHEMBL21453517

SCHEMBL21453517

c1ccc(-c2ccc(N(c3ccc(-c4cccc5c4oc4ccccc45)cc3)c3ccc4c(c3)c3ccc5sc6cccc7c8ccccc8c8ccccc8n4c3c5c67)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.35
PRKDC P78527 1/20 0.32
PTGES2 Q9H7Z7 1/20 0.30
GGPS1 O95749 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21454118 0.95 ALOX5 (0.37) ALOX5PRKDCPTGES2GGPS1
SCHEMBL21454131 0.93 ALOX5 (0.36) ALOX5PRKDCPTGES2GGPS1
SCHEMBL21453513 0.91
SCHEMBL21453508 0.88 ALOX5 (0.43) ALOX5PRKDCPTGES2GGPS1
SCHEMBL21453817 0.88 ALOX5 (0.42) ALOX5PRKDCPTGES2GGPS1
SCHEMBL21453840 0.88 TSPO (0.32)
SCHEMBL21454160 0.87 ALOX5 (0.41) ALOX5PRKDCPTGES2GGPS1
SCHEMBL16850650 0.87 ALOX5 (0.43) ALOX5PRKDCPTGES2GGPS1
SCHEMBL21453504 0.85
SCHEMBL16850735 0.85 ALOX5 (0.43) ALOX5PRKDCPTGES2GGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11038121-B2 9 membered ring carbazole compounds Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-06-15 US disclosed
US-20190312214-A1 9 MEMBERED RING CARBAZOLE COMPOUNDS BEIJING SUMMER SPROUT TECHNOLOGY CO., LTD (CN) 2019-10-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11038121-B2 9 membered ring carbazole compounds SLC25A21, OCIAD2, OXA1L ALOX5 1012/4885PRKDC 4258/4885PTGES2 2226/4885
US-20190312214-A1 9 MEMBERED RING CARBAZOLE COMPOUNDS SLC25A21, OCIAD2, OXA1L ALOX5 1012/4885PRKDC 4258/4885PTGES2 2226/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.