SCHEMBL21453618

SCHEMBL21453618

c1cc(-c2ccc3c(c2)c2cccc4c5ccccc5c5cccc6sc7cccc(c7c65)n3c42)cc(-c2cccc3c2oc2ccccc23)c1

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.42
GGPS1 O95749 1/20 0.36
PRKDC P78527 5/20 0.36
PTGES2 Q9H7Z7 1/20 0.36
PLA2G10 O15496 1/20 0.32
PLA2G2A P14555 1/20 0.32
PLA2G4A P47712 1/20 0.32
PRMT5 O14744 1/20 0.32
WDR77 Q9BQA1 1/20 0.32
BRDT Q58F21 1/20 0.31
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21453610 0.97 ALOX5 (0.45) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL21453784 0.96 ALOX5 (0.44) ALOX5GGPS1PRKDCPTGES2PLA2G10
SCHEMBL21454452 0.95 ALOX5 (0.38) ALOX5GGPS1PRKDCPTGES2PLA2G10
SCHEMBL21454453 0.95 ALOX5 (0.38) ALOX5GGPS1PRKDCPTGES2PLA2G10
SCHEMBL21453637 0.93 ALOX5 (0.46) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL21454160 0.93 ALOX5 (0.41) ALOX5GGPS1PRKDCPTGES2PLA2G10
SCHEMBL21453508 0.89 ALOX5 (0.43) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL21453757 0.88 ALOX5 (0.51) ALOX5GGPS1PRKDCPTGES2PLA2G10
SCHEMBL21453607 0.87 PLA2G2A (0.34) PLA2G10PLA2G2APLA2G4A
SCHEMBL21453608 0.86 AHR (0.33) PLA2G10PLA2G2APLA2G4AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11038121-B2 9 membered ring carbazole compounds Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-06-15 US disclosed
US-20190312214-A1 9 MEMBERED RING CARBAZOLE COMPOUNDS BEIJING SUMMER SPROUT TECHNOLOGY CO., LTD (CN) 2019-10-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11038121-B2 9 membered ring carbazole compounds SLC25A21, OCIAD2, OXA1L ALOX5 1012/4885GGPS1 1768/4885PRKDC 4258/4885
US-20190312214-A1 9 MEMBERED RING CARBAZOLE COMPOUNDS SLC25A21, OCIAD2, OXA1L ALOX5 1012/4885GGPS1 1768/4885PRKDC 4258/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.