Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.33 |
| ▸ | AKT1 | P31749 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12991568 | 0.72 | USP1 (0.38) | RPS6KB1AKT1PDE10A | |
| SCHEMBL14397368 | 0.71 | RPS6KB1 (0.31) | RPS6KB1AKT1 | |
| SCHEMBL1304289 | 0.71 | CCNE1 (0.31) | — | |
| SCHEMBL859562 | 0.70 | — | — | |
| SCHEMBL21449340 | 0.70 | GPR119 (0.37) | — | |
| Hydrochloric Acid SCHEMBL3527705 | 0.69 | RPS6KB1 (0.30) | RPS6KB1AKT1 | |
| SCHEMBL26627790 | 0.68 | ESR1 (0.34) | RPS6KB1AKT1 | |
| SCHEMBL31483563 | 0.68 | — | — | |
| SCHEMBL25159804 | 0.68 | USP1 (0.32) | — | |
| SCHEMBL21453298 | 0.68 | CNR2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019195846-A1 | IMIDAZOPIPERAZINONE INHIBITORS OF TRANSCRIPTION ACTIVATING PROTEINS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2019-10-10 | — | — | WO | disclosed |