SCHEMBL21453764

SCHEMBL21453764

c1ccc(-c2ccc(N(c3ccc(-c4ccccc4)cc3)c3ccc(-c4ccc5c(c4)c4cccc6c7ccccc7c7ccccc7c7ccccc7n5c64)cc3)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSPO P30536 6/20 0.45
NPY5R Q15761 2/20 0.35
POLB P06746 2/20 0.35
KDM4E B2RXH2 2/20 0.35
MEN1 O00255 2/20 0.35
ALDH1A1 P00352 2/20 0.35
MAPT P10636 2/20 0.35
HPGD P15428 2/20 0.35
HTT P42858 2/20 0.35
KMT2A Q03164 2/20 0.35
DNM1 Q05193 1/20 0.34
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32
NR4A2 P43354 2/20 0.32
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32
PLA2G2A P14555 1/20 0.31
PLA2G4A P47712 1/20 0.31
APP P05067 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20363904 0.99 TSPO (0.46) TSPONPY5RPOLBKDM4EMEN1
SCHEMBL21454210 0.94 TSPO (0.40) TSPONPY5RPOLBKDM4EMEN1
SCHEMBL20363882 0.93 TSPO (0.44) TSPONPY5RPOLBKDM4EMEN1
SCHEMBL16842945 0.92 TSPO (0.38) TSPOPOLBKDM4EMEN1ALDH1A1
SCHEMBL19541168 0.91 TSPO (0.40) TSPONPY5RPOLBKDM4EMEN1
SCHEMBL20363858 0.91 TSPO (0.40) TSPONPY5RKDM4EALDH1A1MAPT
SCHEMBL21454043 0.91 TSPO (0.45) TSPONPY5RPOLBKDM4EMEN1
SCHEMBL16850769 0.91 KDM4E (0.41) TSPONPY5RPOLBKDM4EMEN1
SCHEMBL16850686 0.91 L3MBTL1 (0.45) TSPONPY5RPOLBKDM4EMEN1
SCHEMBL16850694 0.91 L3MBTL1 (0.45) TSPONPY5RPOLBKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11038121-B2 9 membered ring carbazole compounds Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-06-15 US disclosed
US-20190312214-A1 9 MEMBERED RING CARBAZOLE COMPOUNDS BEIJING SUMMER SPROUT TECHNOLOGY CO., LTD (CN) 2019-10-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11038121-B2 9 membered ring carbazole compounds SLC25A21, OCIAD2, OXA1L TSPO 136/4885NPY5R 3583/4885POLB 3689/4885
US-20190312214-A1 9 MEMBERED RING CARBAZOLE COMPOUNDS SLC25A21, OCIAD2, OXA1L TSPO 136/4885NPY5R 3583/4885POLB 3689/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.