Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1B | Q01064 | 4/20 | 0.34 |
| ▸ | PDE1A | P54750 | 4/20 | 0.34 |
| ▸ | PDE1C | Q14123 | 4/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | PDE9A | O76083 | 1/20 | 0.30 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22803238 | 0.88 | ADORA1 (0.36) | TMIGD3ADORA1 | |
| SCHEMBL21435084 | 0.83 | BRS3 (0.33) | PDE1BCSF1RDAO | |
| SCHEMBL21449326 | 0.83 | MAPK1 (0.33) | PDE1BCSF1RMAPK1 | |
| Hydrochloric Acid SCHEMBL21435225 | 0.81 | CSF1R (0.33) | PDE1BCSF1RMAPK1 | |
| SCHEMBL21453308 | 0.80 | CSF1R (0.37) | PDE1BCSF1RPDE9A | |
| SCHEMBL17619231 | 0.77 | MAPK1 (0.39) | PDE1BPDE1APDE1CCSF1RMAPK1 | |
| SCHEMBL15893921 | 0.73 | CASP3 (0.34) | PDE1BPDE1APDE1CCSF1RMAPK1 | |
| SCHEMBL21435151 | 0.73 | ALDH1A1 (0.36) | CSF1RMAPK1PDE9A | |
| SCHEMBL21051383 | 0.71 | PDE4B (0.45) | MAPK1 | |
| SCHEMBL19398933 | 0.71 | PDE1B (0.35) | PDE1BPDE1APDE1CMAPK1PDE9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019195846-A1 | IMIDAZOPIPERAZINONE INHIBITORS OF TRANSCRIPTION ACTIVATING PROTEINS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2019-10-10 | — | — | WO | disclosed |