SCHEMBL21453795

SCHEMBL21453795

c1ccc2cc(-c3c4ccccc4c(-c4ccc5c(c4)c4cccc6c7cccc8sc9cccc(c%10ccccc%10n5c64)c9c87)c4ccccc34)ccc2c1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 1/20 0.33
HSD17B2 P37059 1/20 0.33
S1PR4 O95977 2/20 0.32
S1PR5 Q9H228 2/20 0.32
TUBB4A P04350 1/20 0.32
TUBB P07437 1/20 0.32
TUBA3C P0DPH7 1/20 0.32
TUBA1B P68363 1/20 0.32
TUBA4A P68366 1/20 0.32
TUBB4B P68371 1/20 0.32
TUBB3 Q13509 1/20 0.32
TUBB2A Q13885 1/20 0.32
TUBB8 Q3ZCM7 1/20 0.32
TUBA3E Q6PEY2 1/20 0.32
TUBA1A Q71U36 1/20 0.32
TUBA1C Q9BQE3 1/20 0.32
TUBB6 Q9BUF5 1/20 0.32
TUBB2B Q9BVA1 1/20 0.32
TUBB1 Q9H4B7 1/20 0.32
MAPK9 P45984 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21454114 0.97 HSD17B1 (0.36) HSD17B1HSD17B2S1PR4S1PR5TUBB4A
SCHEMBL21454111 0.95 HSD17B1 (0.31) HSD17B1HSD17B2S1PR4S1PR5MAPK9
SCHEMBL21453792 0.95 HSD17B1 (0.37) HSD17B1HSD17B2S1PR4S1PR5TUBB4A
SCHEMBL21453842 0.93 S1PR4 (0.30) HSD17B1HSD17B2S1PR4S1PR5
SCHEMBL21454055 0.92 HSD17B1 (0.35) HSD17B1HSD17B2S1PR4S1PR5
SCHEMBL21454110 0.91 HSD17B1 (0.35) HSD17B1HSD17B2S1PR4S1PR5PMM2
SCHEMBL21453841 0.90 HSD17B1 (0.33) HSD17B1HSD17B2
SCHEMBL21453796 0.88 FLT3 (0.32) PTGES
SCHEMBL21453837 0.88 HSD17B1 (0.34) HSD17B1HSD17B2S1PR4S1PR5TUBB4A
SCHEMBL21453597 0.87 HSD17B1 (0.39) HSD17B1HSD17B2TUBB4ATUBBTUBA3C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11038121-B2 9 membered ring carbazole compounds Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-06-15 US disclosed
US-20190312214-A1 9 MEMBERED RING CARBAZOLE COMPOUNDS BEIJING SUMMER SPROUT TECHNOLOGY CO., LTD (CN) 2019-10-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11038121-B2 9 membered ring carbazole compounds SLC25A21, OCIAD2, OXA1L HSD17B1 1876/4885HSD17B2 1541/4885S1PR4 2804/4885
US-20190312214-A1 9 MEMBERED RING CARBAZOLE COMPOUNDS SLC25A21, OCIAD2, OXA1L HSD17B1 1876/4885HSD17B2 1541/4885S1PR4 2804/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.