SCHEMBL21454110

SCHEMBL21454110

c1ccc2cc(-c3ccc4cc(-c5ccc6c(c5)c5cccc7c8ccccc8c8cccc9sc%10cccc(c%10c98)n6c75)ccc4c3)ccc2c1

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 1/20 0.35
HSD17B2 P37059 1/20 0.35
S1PR4 O95977 3/20 0.32
S1PR5 Q9H228 3/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP1A2 P05177 1/20 0.32
THRB P10828 1/20 0.32
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.32
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
ALOX5 P09917 1/20 0.31
PMM2 O15305 1/20 0.30
MPI P34949 1/20 0.30
PHOSPHO1 Q8TCT1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21454111 0.95 HSD17B1 (0.31) HSD17B1HSD17B2S1PR4S1PR5ALDH1A1
SCHEMBL21453792 0.95 HSD17B1 (0.37) HSD17B1HSD17B2S1PR4S1PR5ALDH1A1
SCHEMBL21454055 0.94 HSD17B1 (0.35) HSD17B1HSD17B2S1PR4S1PR5
SCHEMBL21453837 0.91 HSD17B1 (0.34) HSD17B1HSD17B2S1PR4S1PR5ALDH1A1
SCHEMBL21453795 0.91 HSD17B1 (0.33) HSD17B1HSD17B2S1PR4S1PR5ALDH1A1
SCHEMBL21454106 0.90 PMM2 (0.33) PMM2MPIPHOSPHO1
SCHEMBL21453490 0.90 KDM4E (0.30) ALDH1A1HPGD
SCHEMBL21454114 0.90 HSD17B1 (0.36) HSD17B1HSD17B2S1PR4S1PR5
SCHEMBL21453775 0.89 TSPO (0.34)
SCHEMBL21453491 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11038121-B2 9 membered ring carbazole compounds Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-06-15 US disclosed
US-20190312214-A1 9 MEMBERED RING CARBAZOLE COMPOUNDS BEIJING SUMMER SPROUT TECHNOLOGY CO., LTD (CN) 2019-10-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11038121-B2 9 membered ring carbazole compounds SLC25A21, OCIAD2, OXA1L HSD17B1 1876/4885HSD17B2 1541/4885S1PR4 2804/4885
US-20190312214-A1 9 MEMBERED RING CARBAZOLE COMPOUNDS SLC25A21, OCIAD2, OXA1L HSD17B1 1876/4885HSD17B2 1541/4885S1PR4 2804/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.