Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 19/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21454711 | 0.79 | STING1 (0.52) | STING1 | |
| SCHEMBL21454834 | 0.79 | STING1 (0.55) | STING1 | |
| SCHEMBL30500999 | 0.79 | STING1 (0.55) | STING1 | |
| SCHEMBL21405800 | 0.78 | STING1 (0.44) | STING1 | |
| SCHEMBL30501006 | 0.78 | STING1 (0.69) | STING1 | |
| SCHEMBL30501004 | 0.78 | STING1 (0.69) | STING1 | |
| SCHEMBL30416428 | 0.78 | STING1 (0.44) | STING1 | |
| SCHEMBL21437118 | 0.78 | STING1 (0.69) | STING1 | |
| SCHEMBL21437056 | 0.77 | STING1 (0.56) | STING1 | |
| SCHEMBL21405985 | 0.77 | ALDH1A1 (0.39) | STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019195063-A1 | AZA-BENZOTHIOPHENE COMPOUNDS AS STING AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2019-10-10 | — | — | WO | disclosed |