Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21455708 | 0.81 | TBXAS1 (0.41) | TBXAS1PKMMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23229056 | 0.79 | TBXAS1 (0.42) | TBXAS1PKMMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21455527 | 0.79 | TBXAS1 (0.35) | TBXAS1PKMSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL24200273 | 0.79 | TBXAS1 (0.35) | TBXAS1PKMSMN1; SMN2LMNACYP4F2 | |
| SCHEMBL24199899 | 0.79 | TBXAS1 (0.35) | TBXAS1PKMSMN1; SMN2L3MBTL1ADORA3 | |
| SCHEMBL24199896 | 0.79 | TBXAS1 (0.34) | TBXAS1PKMSMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL21455225 | 0.78 | TBXAS1 (0.34) | TBXAS1PKMMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21455172 | 0.76 | TBXAS1 (0.35) | TBXAS1PKMALDH1A1KDM4EHPGD | |
| SCHEMBL23425579 | 0.76 | TBXAS1 (0.33) | TBXAS1PKM | |
| SCHEMBL24200110 | 0.76 | TBXAS1 (0.33) | TBXAS1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019195720-A1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2019-10-10 | — | — | WO | disclosed |