Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24200273 | 0.93 | TBXAS1 (0.35) | TBXAS1PKMAKR1C3AKR1C2SMN1; SMN2 | |
| SCHEMBL21455527 | 0.85 | TBXAS1 (0.35) | TBXAS1PKMAKR1C3AKR1C2SMN1; SMN2 | |
| SCHEMBL24199896 | 0.84 | TBXAS1 (0.34) | TBXAS1PKMAKR1C3AKR1C2SMN1; SMN2 | |
| SCHEMBL24200110 | 0.81 | TBXAS1 (0.33) | TBXAS1PKM | |
| SCHEMBL21455148 | 0.81 | TBXAS1 (0.37) | TBXAS1PKMAKR1C3AKR1C2SMN1; SMN2 | |
| SCHEMBL25895072 | 0.81 | TBXAS1 (0.37) | TBXAS1PKMAKR1C3AKR1C2SMN1; SMN2 | |
| SCHEMBL24200130 | 0.80 | TBXAS1 (0.39) | TBXAS1PKMSMN1; SMN2USP2GAA | |
| SCHEMBL21455186 | 0.79 | TBXAS1 (0.37) | TBXAS1PKMAKR1C3AKR1C2SMN1; SMN2 | |
| SCHEMBL21455145 | 0.79 | TBXAS1 (0.36) | TBXAS1PKMAKR1C3AKR1C2SMN1; SMN2 | |
| SCHEMBL23656672 | 0.79 | TBXAS1 (0.36) | TBXAS1PKMAKR1C3AKR1C2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939658-A1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-01-19 | — | — | EP | disclosed |