SCHEMBL214554

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL217029	0.92	WEE1 (0.58)	WEE1LCKSRCKDRPLK1
	SCHEMBL8514564	0.91	WEE1 (0.51)	WEE1LCKSRCKDRPLK1
	SCHEMBL8510633	0.89	ADRA2A (0.46)	WEE1LCKSRCKDRPLK1
	SCHEMBL8512238	0.89	ADRA2A (0.46)	WEE1LCKSRCKDRPLK1
	SCHEMBL8513247	0.89	LCK (0.54)	WEE1LCKSRCKDRPLK1
	SCHEMBL8514111	0.89	WEE1 (0.52)	WEE1LCKSRCKDRPLK1
	SCHEMBL215998	0.89	WEE1 (0.55)	WEE1LCKSRCKDRPLK1
	SCHEMBL187898	0.88	TNK2 (0.48)	WEE1LCKSRCKDRJAK3
	SCHEMBL8514433	0.87	WEE1 (0.53)	WEE1KDRPLK1KITKCNH2
	SCHEMBL8514666	0.87	JAK3 (0.43)	WEE1LCKSRCKDRPLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.