Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29838212 | 0.83 | GPR119 (0.36) | KDM4CNPC1RAB9AMEN1KMT2A | |
| SCHEMBL21405213 | 0.83 | GPR119 (0.36) | KDM4CNPC1RAB9AMEN1KMT2A | |
| SCHEMBL21456466 | 0.81 | KDM4C (0.43) | KDM4CNPC1RAB9AL3MBTL1MEN1 | |
| SCHEMBL23205347 | 0.75 | OPRM1 (0.40) | OPRM1HTR2AHTR2CHTR2B | |
| SCHEMBL29790382 | 0.73 | GPR119 (0.35) | — | |
| SCHEMBL7470872 | 0.64 | MEN1 (0.36) | KDM4CNPC1RAB9AL3MBTL1MEN1 | |
| SCHEMBL21456183 | 0.63 | OPRM1 (0.41) | RAB9AL3MBTL1MEN1KMT2AOPRM1 | |
| SCHEMBL21405149 | 0.62 | OPRM1 (0.42) | L3MBTL1OPRM1 | |
| SCHEMBL18095238 | 0.62 | KMT2A (0.45) | KDM4CNPC1RAB9AMEN1KMT2A | |
| SCHEMBL18095237 | 0.62 | KMT2A (0.45) | KDM4CNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021067606-A1 | BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2021-04-08 | — | — | WO | disclosed |
| WO-2019195201-A1 | BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2019-10-10 | — | — | WO | disclosed |