Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Biphenyl. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL2257004 | 0.97 | ALDH1A1 (0.47) | ALDH1A1FFAR3LCKFYNCES2 | |
| Acetic Acid SCHEMBL28848294 | 0.97 | ALDH1A1 (0.53) | ALDH1A1FFAR3LCKFYNCES2 | |
| Acetic Acid SCHEMBL27642452 | 0.97 | ALDH1A1 (0.53) | ALDH1A1FFAR3LCKFYNCES2 | |
| Acetone SCHEMBL26104187 | 0.87 | ALDH1A1 (0.57) | ALDH1A1CES2CES1HSD11B1EPHX1 | |
| Bicarbonate SCHEMBL10775900 | 0.87 | ALDH1A1 (0.57) | ALDH1A1CES2CES1HSD11B1EPHX1 | |
| Biphenyl SCHEMBL2169497 | 0.87 | ALDH1A1 (0.57) | ALDH1A1CES2CES1HSD11B1EPHX1 | |
| Bicarbonate SCHEMBL7025736 | 0.87 | ALDH1A1 (0.57) | ALDH1A1CES2CES1HSD11B1EPHX1 | |
| Bicarbonate SCHEMBL10581815 | 0.87 | ALDH1A1 (0.57) | ALDH1A1CES2CES1HSD11B1EPHX1 | |
| Biphenyl SCHEMBL2145778 | 0.85 | ALDH1A1 (0.47) | ALDH1A1CES2CES1HSD11B1EPHX1 | |
| Methacrylic Acid SCHEMBL4122308 | 0.84 | ALDH1A1 (0.40) | ALDH1A1CES2CES1HSD11B1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109456912-A | The bacillus of one plant of degradable aphthenic acids and its application | 东北师范大学 | 2019-03-12 | — | — | CN | claimed |
| CN-105524861-A | A bacillus strain capable of degrading naphthenic acids and applications thereof | UNIV NORTHEAST | 2016-04-27 | — | — | CN | claimed |
| CN-101260051-A | Biodegradable choline-like ionic liquid | INST PROCESS ENG CAS (CN) | 2008-09-10 | — | — | CN | claimed |
| CN-101050185-A | Ion liquid of quaternaries of naphthenic acid | INST OF PROCEDUE ENGINEERING C (CN) | 2007-10-10 | — | — | CN | claimed |
| US-12410358-B2 | Organic acid-based enhanced waterflooding | UNIVERSITY OF WYOMING (US) | 2025-09-09 | — | — | US | disclosed |
| US-20230064447-A1 | ORGANIC ACID-BASED ENHANCED WATERFLOODING | UNIVERSITY OF WYOMING | 2023-03-02 | — | — | US | disclosed |
| US-11479712-B2 | Organic acid-based enhanced waterflooding | UNIVERSITY OF WYOMING (US) | 2022-10-25 | — | — | US | disclosed |
| CN-115103840-A | Substituted thiophenecarboxamides, thiophenecarboxylic acids and derivatives thereof | 拜耳公司 | 2022-09-23 | — | — | CN | disclosed |
| US-20210054259-A1 | ORGANIC ACID-BASED ENHANCED WATERFLOODING | UNIVERSITY OF WYOMING | 2021-02-25 | — | — | US | disclosed |
| US-10844274-B2 | Organic acid-based enhanced waterflooding | UNIVERSITY OF WYOMING (US) | 2020-11-24 | — | — | US | disclosed |
| CN-106232182-B | S1P3 antagonist | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2019-11-01 | — | — | CN | disclosed |
| US-20190316026-A1 | ORGANIC ACID-BASED ENHANCED WATERFLOODING | UNIVERSITY OF WYOMING | 2019-10-17 | — | — | US | disclosed |
| EP-0823656-B1 | Silver halide photographic light sensitive material | KONISHIROKU PHOTO IND (JP) | 2002-04-10 | — | — | EP | disclosed |
| CN-1332726-A | Pyrrolidine compounds and pharmaceutical use thereof | YOSHITOMI PHARMACEUTICAL (JP) | 2002-01-23 | — | — | CN | disclosed |
| CN-1330637-A | Compounds useful in treatment of infammatory diseases | GLAXO GROUP LTD (GB) | 2002-01-09 | — | — | CN | disclosed |
| US-20010041302-A1 | Chemically amplified resist composition containing low molecular weight additives | SK MATERIALS PERFORMANCE CO., LTD. (KR) | 2001-11-15 | — | — | US | disclosed |
| EP-1126320-A2 | Chemically amplified resist composition containing low molecular weight additives | Korea Kumho Petrochemical Co. Ltd. (KR) | 2001-08-22 | — | — | EP | disclosed |
| US-5985530-A | MULTILAYER PHOTOGRAPHIC FILM WITH COLLOID LAYER | KONICA CORPORATION (JP) | 1999-11-16 | — | — | US | disclosed |
| EP-0921432-A1 | Silver halide light-sensitive photographic comprising a phosphazene compound | KONICA CORPORATION (JP) | 1999-06-09 | — | — | EP | disclosed |
| EP-0823656-A2 | Silver halide photographic light sensitive material | KONICA CORPORATION (JP) | 1998-02-11 | — | — | EP | disclosed |