Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10784791 | 0.88 | ALDH1A1 (0.53) | ALDH1A1CES2CES1HSD11B1EPHX1 | |
| Biphenyl SCHEMBL2145661 | 0.85 | ALDH1A1 (0.50) | ALDH1A1CES2CES1HSD11B1EPHX1 | |
| Acetone SCHEMBL26104187 | 0.84 | ALDH1A1 (0.57) | ALDH1A1CES2CES1HSD11B1EPHX1 | |
| Biphenyl SCHEMBL2257004 | 0.82 | ALDH1A1 (0.47) | ALDH1A1CES2CES1HSD11B1EPHX1 | |
| SCHEMBL11183856 | 0.82 | CES2 (0.48) | ALDH1A1CES2CES1HSD11B1EPHX1 | |
| Biphenyl SCHEMBL688111 | 0.82 | ALDH1A1 (0.47) | ALDH1A1CES2CES1HSD11B1EPHX1 | |
| Acetic Acid SCHEMBL27642452 | 0.81 | ALDH1A1 (0.53) | ALDH1A1CES2CES1HSD11B1EPHX1 | |
| Acetic Acid SCHEMBL28848294 | 0.81 | ALDH1A1 (0.53) | ALDH1A1CES2CES1HSD11B1EPHX1 | |
| Acetamide SCHEMBL28324196 | 0.79 | ALDH1A1 (0.50) | ALDH1A1CES2CES1HSD11B1EPHX1 | |
| Bicarbonate SCHEMBL7025736 | 0.78 | ALDH1A1 (0.57) | ALDH1A1CES2CES1HSD11B1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8580384-B2 | Dielectric materials and methods of preparation and use thereof | POLYERA CORPORATION (US) | 2013-11-12 | — | — | US | disclosed |
| US-20110175089-A1 | Dielectric Materials and Methods of Preparation and Use Thereof | FLEXTERRA, INC. | 2011-07-21 | — | — | US | disclosed |
| WO-2011088343-A2 | DIELECTRIC MATERIALS AND METHODS OF PREPARATION AND USE THEREOF | POLYERA CORPORATION (US) | 2011-07-21 | — | — | WO | disclosed |