Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | PER2 | O15055 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.33 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31048617 | 0.85 | RAB9A (0.38) | ESR1KMT2ATSHRMAPK1HSD17B10 | |
| SCHEMBL28436555 | 0.78 | ESR1 (0.50) | ESR1KMT2ATSHRMAPK1HSD17B10 | |
| SCHEMBL7238334 | 0.78 | KDM4E (0.41) | KMT2ATSHRHSD17B10L3MBTL1MEN1 | |
| SCHEMBL7439630 | 0.72 | TSHR (0.35) | ESR1KMT2ATSHRS1PR1L3MBTL1 | |
| SCHEMBL21475502 | 0.71 | L3MBTL1 (0.32) | KMT2AL3MBTL1MEN1PPARGPPARA | |
| SCHEMBL21456940 | 0.70 | ESR1 (0.45) | ESR1KMT2ATSHRMAPK1HSD17B10 | |
| SCHEMBL11685337 | 0.66 | L3MBTL1 (0.36) | KMT2ATSHRL3MBTL1RAB9AMEN1 | |
| SCHEMBL7157659 | 0.66 | CA12 (0.47) | KMT2ATSHRL3MBTL1HTTMEN1 | |
| SCHEMBL3084153 | 0.65 | USP2 (0.45) | KMT2ATSHRMAPK1MEN1LMNA | |
| SCHEMBL15414378 | 0.65 | NR1I2 (0.37) | ESR1S1PR1L3MBTL1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3553061-A1 | NEW INHIBITORS OF BONE RESORPTION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2019-10-16 | — | — | EP | disclosed |