Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOCK5 | Q9H7D0 | 8/20 | 1.00 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MCHR2 | Q969V1 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21456954 | 1.00 | DOCK5 (1.00) | DOCK5FAAHSIGMAR1ALDH1A1HTT | |
| SCHEMBL21481081 | 0.85 | DOCK5 (0.87) | DOCK5SIGMAR1CYP3A4CYP2D6TSHR | |
| SCHEMBL21456939 | 0.85 | DOCK5 (0.87) | DOCK5SIGMAR1CYP3A4CYP2D6TSHR | |
| SCHEMBL21456937 | 0.85 | DOCK5 (0.87) | DOCK5SIGMAR1CYP3A4CYP2D6TSHR | |
| SCHEMBL21481075 | 0.85 | DOCK5 (0.76) | DOCK5SIGMAR1CYP3A4CYP2D6 | |
| SCHEMBL21456953 | 0.84 | DOCK5 (1.00) | DOCK5FAAHSIGMAR1 | |
| SCHEMBL21456951 | 0.84 | DOCK5 (1.00) | DOCK5FAAHSIGMAR1 | |
| SCHEMBL21456949 | 0.83 | DOCK5 (1.00) | DOCK5SIGMAR1 | |
| SCHEMBL21456947 | 0.83 | DOCK5 (1.00) | DOCK5SIGMAR1 | |
| SCHEMBL21475461 | 0.83 | DOCK5 (0.82) | DOCK5SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019197659-A1 | NEW INHIBITORS OF BONE RESORPTION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2019-10-17 | — | — | WO | disclosed |
| EP-3553061-A1 | NEW INHIBITORS OF BONE RESORPTION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2019-10-16 | — | — | EP | disclosed |