Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOCK5 | Q9H7D0 | 8/20 | 1.00 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21456959 | 1.00 | DOCK5 (1.00) | DOCK5OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL21456937 | 0.88 | DOCK5 (0.87) | DOCK5OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL21456939 | 0.88 | DOCK5 (0.87) | DOCK5OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL21481081 | 0.88 | DOCK5 (0.87) | DOCK5OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL21475486 | 0.87 | DOCK5 (0.77) | DOCK5KDM4EALDH1A1SIGMAR1MEN1 | |
| SCHEMBL21456947 | 0.86 | DOCK5 (1.00) | DOCK5SIGMAR1CHRM3 | |
| SCHEMBL21456949 | 0.86 | DOCK5 (1.00) | DOCK5SIGMAR1CHRM3 | |
| SCHEMBL21456951 | 0.84 | DOCK5 (1.00) | DOCK5OPRL1SIGMAR1MEN1KMT2A | |
| SCHEMBL21456953 | 0.84 | DOCK5 (1.00) | DOCK5OPRL1SIGMAR1MEN1KMT2A | |
| SCHEMBL21475461 | 0.83 | DOCK5 (0.82) | DOCK5SIGMAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019197659-A1 | NEW INHIBITORS OF BONE RESORPTION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2019-10-17 | — | — | WO | disclosed |
| EP-3553061-A1 | NEW INHIBITORS OF BONE RESORPTION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2019-10-16 | — | — | EP | disclosed |