SCHEMBL21457166

SCHEMBL21457166

CCc1ccc(/C=C(\C#N)C(=O)OC(C)C)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.57
KDM4E B2RXH2 2/20 0.56
KMT2A Q03164 2/20 0.56
HPGD P15428 1/20 0.56
MAPT P10636 4/20 0.50
PTP4A3 O75365 1/20 0.50
PTP4A2 Q12974 1/20 0.50
PTP4A1 Q93096 1/20 0.50
IDE P14735 2/20 0.49
LMNA P02545 1/20 0.47
RAB9A P51151 2/20 0.45
MEN1 O00255 1/20 0.45
NPC1 O15118 1/20 0.45
MAPK1 P28482 1/20 0.45
CASP3 P42574 1/20 0.45
SENP8 Q96LD8 1/20 0.45
SENP7 Q9BQF6 1/20 0.45
SENP6 Q9GZR1 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21457168 1.00 ALDH1A1 (0.57) ALDH1A1KDM4EKMT2AHPGDMAPT
SCHEMBL21457546 0.85 ALDH1A1 (0.56) ALDH1A1KDM4EKMT2AMAPTPTP4A3
SCHEMBL21457547 0.85 ALDH1A1 (0.56) ALDH1A1KDM4EKMT2AMAPTPTP4A3
SCHEMBL21457591 0.84 ALDH1A1 (0.61) ALDH1A1KDM4EKMT2AHPGDMAPT
SCHEMBL21457572 0.84 ALDH1A1 (0.61) ALDH1A1KDM4EKMT2AMAPTPTP4A3
SCHEMBL21457576 0.84 ALDH1A1 (0.61) ALDH1A1KDM4EKMT2AMAPTPTP4A3
SCHEMBL21457632 0.84 ALDH1A1 (0.60) ALDH1A1KDM4EKMT2AHPGDMAPT
SCHEMBL21457594 0.84 ALDH1A1 (0.61) ALDH1A1KDM4EKMT2AHPGDMAPT
SCHEMBL21457628 0.84 ALDH1A1 (0.60) ALDH1A1KDM4EKMT2AHPGDMAPT
SCHEMBL6928912 0.83 ALDH1A1 (0.60) ALDH1A1KDM4EKMT2AHPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3553097-B1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORP (JP) 2022-05-04 EP disclosed
US-11225540-B2 Copolymer and optical film using same TOSOH CORPORATION (JP) 2022-01-18 US disclosed
CN-110248971-B Copolymer and optical film using the same 东曹株式会社 2021-11-02 CN disclosed
US-20200095358-A1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORPORATION (JP) 2020-03-26 US disclosed
EP-3553097-A1 COPOLYMER AND OPTICAL FILM USING SAME Tosoh Corporation (JP) 2019-10-16 EP disclosed
CN-110248971-A Copolymer and the optical film for using the copolymer 东曹株式会社 2019-09-17 CN disclosed