SCHEMBL21457572

SCHEMBL21457572

Cc1ccc(/C=C(\C#N)C(=O)OC(C)C)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.61
PTP4A3 O75365 1/20 0.53
PTP4A2 Q12974 1/20 0.53
PTP4A1 Q93096 1/20 0.53
MAPT P10636 3/20 0.50
IDE P14735 2/20 0.50
KDM4E B2RXH2 1/20 0.50
RAB9A P51151 2/20 0.47
EGFR P00533 1/20 0.47
ERBB2 P04626 1/20 0.47
TP53 P04637 1/20 0.46
KMT2A Q03164 2/20 0.46
MEN1 O00255 1/20 0.45
NPC1 O15118 1/20 0.45
MAPK1 P28482 1/20 0.45
CASP3 P42574 1/20 0.45
SENP8 Q96LD8 1/20 0.45
SENP7 Q9BQF6 1/20 0.45
SENP6 Q9GZR1 1/20 0.45
TDP1 Q9NUW8 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21457576 1.00 ALDH1A1 (0.61) ALDH1A1PTP4A3PTP4A2PTP4A1MAPT
SCHEMBL21457591 0.88 ALDH1A1 (0.61) ALDH1A1PTP4A3PTP4A2PTP4A1MAPT
SCHEMBL21457594 0.88 ALDH1A1 (0.61) ALDH1A1PTP4A3PTP4A2PTP4A1MAPT
SCHEMBL21457141 0.87 ALDH1A1 (0.60) ALDH1A1PTP4A3PTP4A2PTP4A1MAPT
SCHEMBL21457524 0.87 ALDH1A1 (0.60) ALDH1A1PTP4A3PTP4A2PTP4A1MAPT
SCHEMBL6928912 0.87 ALDH1A1 (0.60) ALDH1A1PTP4A3PTP4A2PTP4A1MAPT
SCHEMBL21457543 0.87 ALDH1A1 (0.60) ALDH1A1PTP4A3PTP4A2PTP4A1MAPT
SCHEMBL21457760 0.87 ALDH1A1 (0.60) ALDH1A1PTP4A3PTP4A2PTP4A1MAPT
SCHEMBL21457526 0.87 ALDH1A1 (0.60) ALDH1A1PTP4A3PTP4A2PTP4A1MAPT
SCHEMBL6928915 0.87 ALDH1A1 (0.60) ALDH1A1PTP4A3PTP4A2PTP4A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3553097-B1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORP (JP) 2022-05-04 EP disclosed
US-11225540-B2 Copolymer and optical film using same TOSOH CORPORATION (JP) 2022-01-18 US disclosed
CN-110248971-B Copolymer and optical film using the same 东曹株式会社 2021-11-02 CN disclosed
US-20200095358-A1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORPORATION (JP) 2020-03-26 US disclosed
EP-3553097-A1 COPOLYMER AND OPTICAL FILM USING SAME Tosoh Corporation (JP) 2019-10-16 EP disclosed
CN-110248971-A Copolymer and the optical film for using the copolymer 东曹株式会社 2019-09-17 CN disclosed