SCHEMBL21457258

SCHEMBL21457258

CCCOC(=O)/C(C#N)=C/c1ccc(Br)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.56
ALDH1A1 P00352 8/20 0.56
KDM4E B2RXH2 2/20 0.56
DNM1 Q05193 3/20 0.56
PTP4A1 Q93096 2/20 0.53
MEN1 O00255 4/20 0.52
KMT2A Q03164 4/20 0.52
MAPK1 P28482 3/20 0.52
L3MBTL1 Q9Y468 3/20 0.52
LMNA P02545 2/20 0.52
USP2 O75604 1/20 0.52
POLB P06746 1/20 0.52
RECQL P46063 1/20 0.52
BLM P54132 1/20 0.52
TP53 P04637 1/20 0.52
S1PR4 O95977 1/20 0.51
S1PR1 P21453 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
PKM P14618 1/20 0.51
HTT P42858 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21457262 1.00 MAPT (0.56) MAPTALDH1A1KDM4EDNM1PTP4A1
SCHEMBL11071019 0.93 ALDH1A1 (0.63) MAPTALDH1A1KDM4EDNM1PTP4A1
SCHEMBL11071030 0.93 ALDH1A1 (0.63) MAPTALDH1A1KDM4EDNM1PTP4A1
SCHEMBL363338 0.89 ALDH1A1 (0.71) MAPTALDH1A1KDM4EPTP4A1MEN1
SCHEMBL363339 0.89 ALDH1A1 (0.71) MAPTALDH1A1KDM4EPTP4A1MEN1
SCHEMBL21457255 0.87 DNM1 (0.60) MAPTALDH1A1KDM4EDNM1PTP4A1
SCHEMBL21457173 0.87 ALDH1A1 (0.61) MAPTALDH1A1KDM4EDNM1PTP4A1
SCHEMBL11417549 0.87 KDM4E (0.58) MAPTALDH1A1KDM4EDNM1
SCHEMBL21457177 0.87 ALDH1A1 (0.61) MAPTALDH1A1KDM4EDNM1PTP4A1
SCHEMBL19835215 0.87 DNM1 (0.60) MAPTALDH1A1KDM4EDNM1PTP4A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3553097-B1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORP (JP) 2022-05-04 EP disclosed
US-11225540-B2 Copolymer and optical film using same TOSOH CORPORATION (JP) 2022-01-18 US disclosed
CN-110248971-B Copolymer and optical film using the same 东曹株式会社 2021-11-02 CN disclosed
US-20200095358-A1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORPORATION (JP) 2020-03-26 US disclosed
EP-3553097-A1 COPOLYMER AND OPTICAL FILM USING SAME Tosoh Corporation (JP) 2019-10-16 EP disclosed