SCHEMBL21457504

SCHEMBL21457504

CCc1cccc(C=CC(=O)c2ccccc2)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 6/20 0.62
▸ MAOB P27338 5/20 0.62
▸ BCHE P06276 3/20 0.62
▸ LMNA P02545 2/20 0.62
▸ CYP1B1 Q16678 2/20 0.62
▸ PLIN1 O60240 1/20 0.62
▸ TNFRSF1A P19438 1/20 0.62
▸ ACHE P22303 1/20 0.62
▸ RECQL P46063 1/20 0.62
▸ PLIN5 Q00G26 1/20 0.62
▸ ABHD5 Q8WTS1 1/20 0.62
▸ HDAC3 O15379 1/20 0.58
▸ HDAC4 P56524 1/20 0.58
▸ HDAC1 Q13547 1/20 0.58
▸ HDAC7 Q8WUI4 1/20 0.58
▸ HDAC2 Q92769 1/20 0.58
▸ HDAC10 Q969S8 1/20 0.58
▸ HDAC11 Q96DB2 1/20 0.58
▸ HDAC8 Q9BY41 1/20 0.58
▸ HDAC6 Q9UBN7 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21457502 1.00 MAPT (0.62) MAPTMAOBBCHELMNACYP1B1
SCHEMBL6396307 0.89 MAOB (0.53) MAPTMAOBBCHELMNACYP1B1
SCHEMBL28068830 0.86 MAOB (0.64) MAPTMAOBBCHELMNACYP1B1
SCHEMBL28068831 0.86 MAOB (0.64) MAPTMAOBBCHELMNACYP1B1
SCHEMBL17083115 0.85 KDM4E (0.62) MAPTLMNAHDAC3HDAC4HDAC1
SCHEMBL28363349 0.85 KDM4E (0.62) MAPTLMNAHDAC3HDAC4HDAC1
SCHEMBL28301215 0.85 MAOB (0.62) MAPTMAOBBCHELMNACYP1B1
SCHEMBL11148436 0.85 MAPT (0.66) MAPTMAOBBCHELMNACYP1B1
SCHEMBL11137146 0.84 MAPT (0.61) MAPTMAOBBCHELMNACYP1B1
SCHEMBL9337829 0.84 P4HB (0.47) MAOBBCHEHDAC4MAOAP4HB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3553097-B1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORP (JP) 2022-05-04 — — EP disclosed
US-11225540-B2 Copolymer and optical film using same TOSOH CORPORATION (JP) 2022-01-18 — — US disclosed
CN-110248971-B Copolymer and optical film using the same 东曹株式会社 2021-11-02 — — CN disclosed
US-20200095358-A1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORPORATION (JP) 2020-03-26 — — US disclosed
EP-3553097-A1 COPOLYMER AND OPTICAL FILM USING SAME Tosoh Corporation (JP) 2019-10-16 — — EP disclosed
CN-110248971-A Copolymer and the optical film for using the copolymer 东曹株式会社 2019-09-17 — — CN disclosed
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