SCHEMBL21457568

SCHEMBL21457568

CC(C)COC(=O)/C(C#N)=C/c1ccc(O)c(C(=O)O)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 3/20 0.57
ALDH1A1 P00352 6/20 0.54
MAPT P10636 5/20 0.54
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
RECQL P46063 2/20 0.51
TDP1 Q9NUW8 2/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
PTP4A3 O75365 1/20 0.50
PTP4A1 Q93096 1/20 0.50
PKM P14618 1/20 0.47
HTT P42858 1/20 0.47
EGFR P00533 1/20 0.47
KDM4E B2RXH2 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
HPGD P15428 1/20 0.46
ALOX15 P16050 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21457570 1.00 DNM1 (0.57) DNM1ALDH1A1MAPTMEN1KMT2A
SCHEMBL21457695 0.91 DNM1 (0.57) DNM1ALDH1A1MAPTMEN1KMT2A
SCHEMBL21457692 0.91 DNM1 (0.57) DNM1ALDH1A1MAPTMEN1KMT2A
SCHEMBL21457530 0.91 DNM1 (0.50) DNM1ALDH1A1MAPTMEN1KMT2A
SCHEMBL21457527 0.91 DNM1 (0.50) DNM1ALDH1A1MAPTMEN1KMT2A
SCHEMBL21457207 0.88 DNM1 (0.74) DNM1ALDH1A1MAPTMEN1KMT2A
SCHEMBL21457211 0.88 DNM1 (0.74) DNM1ALDH1A1MAPTMEN1KMT2A
SCHEMBL13005208 0.87 ALDH1A1 (0.70) DNM1ALDH1A1MAPTMEN1KMT2A
SCHEMBL21457464 0.85 DNM1 (0.65) DNM1ALDH1A1MAPTMEN1KMT2A
SCHEMBL21457700 0.84 ALDH1A1 (0.53) DNM1ALDH1A1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3553097-B1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORP (JP) 2022-05-04 EP disclosed
US-11225540-B2 Copolymer and optical film using same TOSOH CORPORATION (JP) 2022-01-18 US disclosed
CN-110248971-B Copolymer and optical film using the same 东曹株式会社 2021-11-02 CN disclosed
US-20200095358-A1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORPORATION (JP) 2020-03-26 US disclosed
EP-3553097-A1 COPOLYMER AND OPTICAL FILM USING SAME Tosoh Corporation (JP) 2019-10-16 EP disclosed