SCHEMBL21457760

SCHEMBL21457760

CC(C)OC(=O)C(C#N)=Cc1ccc(F)cc1

nearest known ligand 0.60

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.60
PTP4A3 O75365 1/20 0.52
PTP4A2 Q12974 1/20 0.52
PTP4A1 Q93096 1/20 0.52
MAPT P10636 4/20 0.51
ATM Q13315 2/20 0.51
GAA P10253 1/20 0.51
HTT P42858 1/20 0.51
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
IDE P14735 2/20 0.49
KDM4E B2RXH2 2/20 0.46
RAB9A P51151 1/20 0.46
HPGD P15428 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
EGFR P00533 1/20 0.46
ERBB2 P04626 1/20 0.46
TP53 P04637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21457757 1.00 ALDH1A1 (0.60) ALDH1A1PTP4A3PTP4A2PTP4A1MAPT
SCHEMBL21457576 0.87 ALDH1A1 (0.61) ALDH1A1PTP4A3PTP4A2PTP4A1MAPT
SCHEMBL21457591 0.87 ALDH1A1 (0.61) ALDH1A1PTP4A3PTP4A2PTP4A1MAPT
SCHEMBL21457594 0.87 ALDH1A1 (0.61) ALDH1A1PTP4A3PTP4A2PTP4A1MAPT
SCHEMBL21457572 0.87 ALDH1A1 (0.61) ALDH1A1PTP4A3PTP4A2PTP4A1MAPT
SCHEMBL21457142 0.85 ALDH1A1 (0.60) ALDH1A1PTP4A3PTP4A2PTP4A1MAPT
SCHEMBL21457526 0.85 ALDH1A1 (0.60) ALDH1A1PTP4A3PTP4A2PTP4A1MAPT
SCHEMBL21457141 0.85 ALDH1A1 (0.60) ALDH1A1PTP4A3PTP4A2PTP4A1MAPT
SCHEMBL21457543 0.85 ALDH1A1 (0.60) ALDH1A1PTP4A3PTP4A2PTP4A1MAPT
SCHEMBL6928912 0.85 ALDH1A1 (0.60) ALDH1A1PTP4A3PTP4A2PTP4A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3553097-B1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORP (JP) 2022-05-04 EP disclosed
US-11225540-B2 Copolymer and optical film using same TOSOH CORPORATION (JP) 2022-01-18 US disclosed
CN-110248971-B Copolymer and optical film using the same 东曹株式会社 2021-11-02 CN disclosed
US-20200095358-A1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORPORATION (JP) 2020-03-26 US disclosed
EP-3553097-A1 COPOLYMER AND OPTICAL FILM USING SAME Tosoh Corporation (JP) 2019-10-16 EP disclosed