SCHEMBL21457676

SCHEMBL21457676

CCOC(=O)/C(C#N)=C/c1ccc(C#N)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PDCD1 Q15116 1/20 0.71
▸ CD274 Q9NZQ7 1/20 0.71
▸ ALDH1A1 P00352 10/20 0.71
▸ MAPT P10636 7/20 0.71
▸ KDM4E B2RXH2 4/20 0.71
▸ PKM P14618 2/20 0.64
▸ HTT P42858 1/20 0.64
▸ KMT2A Q03164 6/20 0.63
▸ MEN1 O00255 4/20 0.63
▸ L3MBTL1 Q9Y468 2/20 0.63
▸ TDP1 Q9NUW8 2/20 0.63
▸ NPC1 O15118 1/20 0.63
▸ MAPK1 P28482 1/20 0.63
▸ CASP3 P42574 1/20 0.63
▸ RAB9A P51151 1/20 0.63
▸ SENP8 Q96LD8 1/20 0.63
▸ SENP7 Q9BQF6 1/20 0.63
▸ SENP6 Q9GZR1 1/20 0.63
▸ CRHBP P24387 1/20 0.60
▸ CRHR2 Q13324 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1237810 1.00 PDCD1 (0.71) PDCD1CD274ALDH1A1MAPTKDM4E
SCHEMBL2879588 1.00 PDCD1 (0.71) PDCD1CD274ALDH1A1MAPTKDM4E
SCHEMBL2139676 0.92 ALDH1A1 (0.81) PDCD1CD274ALDH1A1MAPTKDM4E
SCHEMBL2139678 0.92 ALDH1A1 (0.81) PDCD1CD274ALDH1A1MAPTKDM4E
SCHEMBL4317761 0.92 ALDH1A1 (0.81) PDCD1CD274ALDH1A1MAPTKDM4E
SCHEMBL21457288 0.89 PDCD1 (0.57) PDCD1CD274ALDH1A1MAPTKDM4E
SCHEMBL21457291 0.89 PDCD1 (0.57) PDCD1CD274ALDH1A1MAPTKDM4E
SCHEMBL8998886 0.88 ALDH1A1 (0.74) PDCD1CD274ALDH1A1MAPTKDM4E
SCHEMBL20278911 0.88 ALDH1A1 (0.74) PDCD1CD274ALDH1A1MAPTKDM4E
SCHEMBL8998890 0.88 ALDH1A1 (0.74) PDCD1CD274ALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3553097-B1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORP (JP) 2022-05-04 — — EP disclosed
US-11225540-B2 Copolymer and optical film using same TOSOH CORPORATION (JP) 2022-01-18 — — US disclosed
CN-110248971-B Copolymer and optical film using the same 东曹株式会社 2021-11-02 — — CN disclosed
US-20200095358-A1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORPORATION (JP) 2020-03-26 — — US disclosed
EP-3553097-A1 COPOLYMER AND OPTICAL FILM USING SAME Tosoh Corporation (JP) 2019-10-16 — — EP disclosed
CN-110248971-A Copolymer and the optical film for using the copolymer 东曹株式会社 2019-09-17 — — CN disclosed
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