Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.74 |
| ▸ | MAPT | P10636 | 9/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.74 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.66 |
| ▸ | RAB9A | P51151 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | CASP3 | P42574 | 1/20 | 0.66 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.66 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.66 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.66 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.63 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8998886 | 1.00 | ALDH1A1 (0.74) | ALDH1A1MAPTKDM4EPKMHTT | |
| SCHEMBL20278911 | 1.00 | ALDH1A1 (0.74) | ALDH1A1MAPTKDM4EPKMHTT | |
| SCHEMBL4317761 | 0.95 | ALDH1A1 (0.81) | ALDH1A1MAPTKDM4EPKMHTT | |
| SCHEMBL2139678 | 0.95 | ALDH1A1 (0.81) | ALDH1A1MAPTKDM4EPKMHTT | |
| SCHEMBL2139676 | 0.95 | ALDH1A1 (0.81) | ALDH1A1MAPTKDM4EPKMHTT | |
| SCHEMBL21457173 | 0.90 | ALDH1A1 (0.61) | ALDH1A1MAPTKDM4EPKMHTT | |
| SCHEMBL21457177 | 0.90 | ALDH1A1 (0.61) | ALDH1A1MAPTKDM4EPKMHTT | |
| SCHEMBL268529 | 0.89 | ALDH1A1 (0.72) | ALDH1A1MAPTKDM4EPKMHTT | |
| SCHEMBL10346450 | 0.89 | ALDH1A1 (0.72) | ALDH1A1MAPTKDM4EPKMHTT | |
| SCHEMBL268530 | 0.89 | ALDH1A1 (0.72) | ALDH1A1MAPTKDM4EPKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3553097-B1 | COPOLYMER AND OPTICAL FILM USING SAME | TOSOH CORP (JP) | 2022-05-04 | — | — | EP | disclosed |
| US-11225540-B2 | Copolymer and optical film using same | TOSOH CORPORATION (JP) | 2022-01-18 | — | — | US | disclosed |
| CN-110248971-B | Copolymer and optical film using the same | 东曹株式会社 | 2021-11-02 | — | — | CN | disclosed |
| CN-113416191-A | Method for synthesizing tricyclic framework 2-pyridone/2-pyridine imine compound | 西安交通大学 | 2021-09-21 | — | — | CN | disclosed |
| US-20200095358-A1 | COPOLYMER AND OPTICAL FILM USING SAME | TOSOH CORPORATION (JP) | 2020-03-26 | — | — | US | disclosed |
| EP-3553097-A1 | COPOLYMER AND OPTICAL FILM USING SAME | Tosoh Corporation (JP) | 2019-10-16 | — | — | EP | disclosed |
| US-7947707-B2 | Nitrogenated heterocyclic compound and pharmaceutical composition comprising the same | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2011-05-24 | — | — | US | disclosed |
| US-20090306396-A1 | NITROGENATED HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-12-10 | — | — | US | disclosed |
| US-5554624-A | CONGESTIVE HEART FAILURE; HYPOTENSIVE AGENTS | J. URIACH & CIA. (ES) | 1996-09-10 | — | — | US | disclosed |
| EP-0669333-A1 | New imidazopyridine derivatives as angiotensin II antagonists | J. URIACH & CIA. S.A. (ES) | 1995-08-30 | — | — | EP | disclosed |
| EP-0035363-B1 | INDANE DERIVATIVES, METHODS OF THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | KEFALAS A/S (DK) | 1985-05-02 | — | — | EP | disclosed |
| US-4443448-A | ANALGESICS, ANTIDEPRESSANTS, NEUROLEPTICS | KEFALAS A/S (DK) | 1984-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306396-A1 | NITROGENATED HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | XDH, CBR3, CBR1 | ALDH1A1 280/4885MAPT 3592/4885KDM4E 3294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.