Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL216646 | 1.00 | TSHR (0.33) | TSHRHIF1ALMNAMAPT | |
| SCHEMBL214617 | 1.00 | TSHR (0.33) | TSHRHIF1ALMNAMAPT | |
| SCHEMBL215413 | 0.94 | TSHR (0.34) | TSHRHIF1ALMNA | |
| SCHEMBL214883 | 0.86 | HIF1A (0.33) | HIF1AMAPT | |
| SCHEMBL215741 | 0.85 | TSHR (0.48) | TSHRHIF1AMAPT | |
| SCHEMBL215495 | 0.84 | TSHR (0.34) | TSHRHIF1AMAPT | |
| SCHEMBL217781 | 0.81 | ALDH1A1 (0.33) | LMNA | |
| SCHEMBL215106 | 0.79 | TSHR (0.32) | TSHRHIF1A | |
| SCHEMBL216463 | 0.78 | LMNA (0.37) | LMNA | |
| SCHEMBL745668 | 0.78 | TSHR (0.42) | TSHRHIF1ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2514812-B1 | Fragrance compositions and compounds | GIVAUDAN SA (CH) | 2018-10-03 | — | — | EP | claimed |
| EP-2514812-A2 | Fragrance compositions and compounds | Givaudan Nederland Services B.V. (NL) | 2012-10-24 | — | — | EP | claimed |
| US-8088725-B2 | Fragrance compositions and compounds | GIVAUDAN NEDERLAND SERVICES B.V. (NL) | 2012-01-03 | — | — | US | claimed |
| US-20100132249-A1 | Fragrance Compositions and Compounds | GIVAUDAN NEDERLAND SERVICES B.V. (NL) | 2010-06-03 | — | — | US | claimed |
| EP-2514812-B1 | Fragrance compositions and compounds | GIVAUDAN SA (CH) | 2018-10-03 | — | — | EP | disclosed |
| EP-2514812-A2 | Fragrance compositions and compounds | Givaudan Nederland Services B.V. (NL) | 2012-10-24 | — | — | EP | disclosed |
| US-8088725-B2 | Fragrance compositions and compounds | GIVAUDAN NEDERLAND SERVICES B.V. (NL) | 2012-01-03 | — | — | US | disclosed |
| US-20100132249-A1 | Fragrance Compositions and Compounds | GIVAUDAN NEDERLAND SERVICES B.V. (NL) | 2010-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100132249-A1 | Fragrance Compositions and Compounds | H1-0, H1-10, H1-5 | TSHR 3815/4885HIF1A 931/4885LMNA 2425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.