SCHEMBL214614

SCHEMBL214614

NC(=O)/C=C/c1ccc(O)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.68
F3 P13726 2/20 0.68
CYP2D6 P10635 1/20 0.68
CYP2C9 P11712 1/20 0.68
HSD11B1 P28845 1/20 0.68
ESR1 P03372 3/20 0.65
AKR1B10 O60218 2/20 0.65
AKR1B1 P15121 2/20 0.65
CA12 O43570 2/20 0.65
CA1 P00915 2/20 0.65
CA2 P00918 2/20 0.65
CA7 P43166 2/20 0.65
CA9 Q16790 2/20 0.65
CA14 Q9ULX7 2/20 0.65
PKM P14618 2/20 0.65
CA3 P07451 1/20 0.65
CA4 P22748 1/20 0.65
CA6 P23280 1/20 0.65
DPP4 P27487 1/20 0.65
CA5A P35218 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL214615 1.00 TYR (0.68) TYRF3CYP2D6CYP2C9HSD11B1
SCHEMBL1450230 0.91 F3 (0.52) TYRF3CYP2D6CYP2C9HSD11B1
SCHEMBL7558225 0.82 CYP1B1 (0.53) TYRF3CYP2D6CYP2C9HSD11B1
SCHEMBL7558227 0.82 CYP1B1 (0.53) TYRF3CYP2D6CYP2C9HSD11B1
SCHEMBL3580956 0.81 TYR (1.00) TYRF3CYP2D6CYP2C9HSD11B1
SCHEMBL2198475 0.81 TYR (1.00) TYRF3CYP2D6CYP2C9HSD11B1
SCHEMBL2146080 0.81 TYR (1.00) TYRF3CYP2D6CYP2C9HSD11B1
SCHEMBL12426066 0.80 PELI1 (0.44) TYRF3CYP2D6CYP2C9HSD11B1
SCHEMBL8147578 0.80 CYP1A2 (0.69) MAOBCYP3A4KMT2ARAB9AMMP1
SCHEMBL14941432 0.80 ALDH1A1 (0.48) TYRF3CYP2D6CYP2C9HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240191245-A1 PLANT CELL MATRICES AND METHODS THEREOF CALYXT, INC. (US) 2024-06-13 US claimed
WO-2022198085-A2 PLANT CELL MATRICES AND METHODS THEREOF CALYXT, INC. (US) 2022-09-22 WO claimed
CN-110907575-B Deep annotation method of hydroxycinnamic acid amide in plants 中国科学院大连化学物理研究所 2021-10-08 CN claimed
CN-110907575-A Deep annotation method of hydroxycinnamic acid amide in plants 中国科学院大连化学物理研究所 2020-03-24 CN claimed
EP-0255695-B1 P-HYDROXYCINNAMAMIDE DERIVATIVES AND MELANIN INHIBITOR COMPRISING THE SAME Kao Corporation (JP) 1991-06-12 EP claimed
US-4981680-A P-hydroxycinnamamide derivatives and melanin inhibitor comprising the same KAO CORPORATION (JP) 1991-01-01 US claimed
US-4876084-A FOR SPOTS, FRECKLES AND SUNBURN KAO CORPORATION (JP) 1989-10-24 US claimed
EP-0255695-A2 p-Hydroxycinnamamide derivatives and melanin inhibitor comprising the same Kao Corporation (JP) 1988-02-10 EP claimed
JP-57046915-A None JP disclosed
JP-60190713-A None JP disclosed
US-20260091612-A1 PRINTING INTAGLIO PLATE AND PRODUCTION METHOD THEREOF, AND PRINTING METHOD ASAHI KASEI KABUSHIKI KAISHA (JP) 2026-04-02 US disclosed
CN-121108220-A Imidazole-4-ethylamine-p-hydroxycinnamamide-1-N-beta-D-glucoside as well as preparation method and application thereof 泰州学院 2025-12-12 CN disclosed
CN-121108220-A Imidazole-4-ethylamine-p-hydroxycinnamamide-1-N-beta-D-glucoside as well as preparation method and application thereof 泰州学院 2025-12-12 CN disclosed
EP-4631736-A1 PRINTING INTAGLIO PLATE AND PRODUCTION METHOD THEREFOR, AND PRINTING METHOD Asahi Kasei Kabushiki Kaisha (JP) 2025-10-15 EP disclosed
US-4876084-A FOR SPOTS, FRECKLES AND SUNBURN KAO CORPORATION (JP) 1989-10-24 US disclosed
EP-0255695-A2 p-Hydroxycinnamamide derivatives and melanin inhibitor comprising the same Kao Corporation (JP) 1988-02-10 EP disclosed
EP-0255695-A2 p-Hydroxycinnamamide derivatives and melanin inhibitor comprising the same Kao Corporation (JP) 1988-02-10 EP disclosed
EP-0255695-A2 p-Hydroxycinnamamide derivatives and melanin inhibitor comprising the same Kao Corporation (JP) 1988-02-10 EP disclosed
JP-S60190713-A MELANINE-SUPPRESSING AGENT KAO CORP 1985-09-28 JP disclosed
JP-S5746915-A ANTIALLERGIC AGENT BANYU PHARMACEUT CO LTD 1982-03-17 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091612-A1 PRINTING INTAGLIO PLATE AND PRODUCTION METHOD THEREOF, AND PRINTING METHOD KIT, MC1R, LIFR TYR 367/4885F3 1780/4885CYP2D6 3727/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.