SCHEMBL214615

SCHEMBL214615

NC(=O)C=Cc1ccc(O)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.68
F3 P13726 2/20 0.68
CYP2D6 P10635 1/20 0.68
CYP2C9 P11712 1/20 0.68
HSD11B1 P28845 1/20 0.68
ESR1 P03372 3/20 0.65
AKR1B10 O60218 2/20 0.65
AKR1B1 P15121 2/20 0.65
CA12 O43570 2/20 0.65
CA1 P00915 2/20 0.65
CA2 P00918 2/20 0.65
CA7 P43166 2/20 0.65
CA9 Q16790 2/20 0.65
CA14 Q9ULX7 2/20 0.65
PKM P14618 2/20 0.65
CA3 P07451 1/20 0.65
CA4 P22748 1/20 0.65
CA6 P23280 1/20 0.65
DPP4 P27487 1/20 0.65
CA5A P35218 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL214614 1.00 TYR (0.68) TYRF3CYP2D6CYP2C9HSD11B1
SCHEMBL1450230 0.91 F3 (0.52) TYRF3CYP2D6CYP2C9HSD11B1
SCHEMBL7558225 0.82 CYP1B1 (0.53) TYRF3CYP2D6CYP2C9HSD11B1
SCHEMBL7558227 0.82 CYP1B1 (0.53) TYRF3CYP2D6CYP2C9HSD11B1
SCHEMBL3580956 0.81 TYR (1.00) TYRF3CYP2D6CYP2C9HSD11B1
SCHEMBL2198475 0.81 TYR (1.00) TYRF3CYP2D6CYP2C9HSD11B1
SCHEMBL2146080 0.81 TYR (1.00) TYRF3CYP2D6CYP2C9HSD11B1
SCHEMBL12426066 0.80 PELI1 (0.44) TYRF3CYP2D6CYP2C9HSD11B1
SCHEMBL8147578 0.80 CYP1A2 (0.69) MAOBCYP3A4KMT2ARAB9AMMP1
SCHEMBL14941432 0.80 ALDH1A1 (0.48) TYRF3CYP2D6CYP2C9HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 524 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260132413-A1 AROGENATE DEHYDROGENASE POLYNUCLEOTIDES, POLYPEPTIDES AND METHODS OF USING THE SAME WISCONSIN ALUMNI RES FOUNDATION (US) 2026-05-14 US claimed
US-20250136952-A1 ENGINEERED PREPHENATE DEHYDROGENASES AND AROGENATE DEHYDROGENASES AND METHODS OF USING THE SAME WISCONSIN ALUMNI RESEARCH FOUNDATION 2025-05-01 US claimed
CN-116064608-B Hordeum vulgare agmatine coumaroyl transferase gene HvACT2 and application thereof in improving disease resistance of barley 浙江大学 2025-01-28 CN claimed
US-12134788-B2 Engineered prephenate dehydrogenases and arogenate dehydrogenases and methods of using the same WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2024-11-05 US claimed
CN-118754661-A Preparation method of ceramic tube with large length-diameter ratio LLZTO 江苏新锂元科技有限公司 2024-10-11 CN claimed
CN-118724761-A Preparation method of novel guanidine benzoate derivatives and application of guanidine benzoate derivatives in pancreatitis 天津理工大学 2024-10-01 CN claimed
CN-118203664-A Composition containing at least one natural or synthetic N-alkylamide as active substance and method for producing same 埃利奥诺公司 2024-06-18 CN claimed
US-20230354864-A1 EXTRACT, CONSUMABLE PRODUCT AND METHOD FOR ENRICHING BIOACTIVE METABOLITE IN AN EXTRACT BRIGHTSEED, INC. 2023-11-09 US claimed
US-20230192646-A1 DIHYDRO-CYCLOPENTA-ISOQUINOLINE DERIVATIVES UCB Biopharma SRL (BE) 2023-06-22 US claimed
US-20230159762-A1 NIR TO SWIR FLUORESCENT COMPOUNDS FOR IMAGING AND DETECTION REVVITY HEALTH SCIENCES, INC. 2023-05-25 US claimed
US-5582942-A BINDER RESIN COMPRISES A COPOLYMER INCLUDING A (METH)ACRYLIC ACID ESTER CONTAINING AN AROMATIC RING AND A VINYL MONOMER HAVING ONE TO THREE ACID FUNCTIONAL GROUPS FUJI PHOTO FILM CO., LTD. (JP) 1996-12-10 US claimed
EP-0313346-B1 Cysteine proteinases, production and use GENZYME CORP (US) 1994-03-02 EP claimed
CN-1018152-B The method for preparing melanin inhibitor KAO CORP (JP) 1992-09-09 CN claimed
US-5106621-A Derived from pineapple plant stems; for debridement of burn tissue ROWAN ANDREW D (GB) 1992-04-21 US claimed
EP-0255695-B1 P-HYDROXYCINNAMAMIDE DERIVATIVES AND MELANIN INHIBITOR COMPRISING THE SAME Kao Corporation (JP) 1991-06-12 EP claimed
US-5006433-A Printing plate precursors for electrophotographic plate-making purposes FUJI PHOTO FILM CO., LTD. (JP) 1991-04-09 US claimed
US-4981680-A P-hydroxycinnamamide derivatives and melanin inhibitor comprising the same KAO CORPORATION (JP) 1991-01-01 US claimed
US-4876084-A FOR SPOTS, FRECKLES AND SUNBURN KAO CORPORATION (JP) 1989-10-24 US claimed
CN-87105374-A P-hydroxyl cinnamamide derivative and the melanin inhibitor that contains this derivative 1988-03-09 CN claimed
EP-0255695-A2 p-Hydroxycinnamamide derivatives and melanin inhibitor comprising the same Kao Corporation (JP) 1988-02-10 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132413-A1 AROGENATE DEHYDROGENASE POLYNUCLEOTIDES, POLYPEPTIDES AND METHODS OF USING THE SAME PNP, RNGTT, DPYD TYR 527/4885F3 2243/4885CYP2D6 948/4885
US-20230354864-A1 EXTRACT, CONSUMABLE PRODUCT AND METHOD FOR ENRICHING BIOACTIVE METABOLITE IN AN EXTRACT HCAR2, HNMT, TYR TYR 3/4885F3 2651/4885CYP2D6 1355/4885
US-20230159762-A1 NIR TO SWIR FLUORESCENT COMPOUNDS FOR IMAGING AND DETECTION SMARCD1, SMARCE1, SMARCB1 TYR 1851/4885F3 815/4885CYP2D6 3768/4885
US-20230192646-A1 DIHYDRO-CYCLOPENTA-ISOQUINOLINE DERIVATIVES FCER2, FCGR2A, FCGR1A TYR 1829/4885F3 855/4885CYP2D6 745/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.