Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Dioxane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL1866439 | 0.94 | TTR (0.86) | — | |
| Water SCHEMBL11426218 | 0.94 | TTR (0.86) | — | |
| Dioxane SCHEMBL2427 | 0.94 | — | — | |
| Water SCHEMBL9161357 | 0.94 | TTR (0.86) | — | |
| Dioxane SCHEMBL15882140 | 0.94 | TTR (0.86) | — | |
| Dioxane SCHEMBL23090025 | 0.94 | TTR (0.86) | — | |
| Dioxane SCHEMBL103807 | 0.94 | — | — | |
| Dioxane SCHEMBL129563 | 0.94 | — | — | |
| Dioxane SCHEMBL2832209 | 0.94 | TTR (0.86) | — | |
| Dioxane SCHEMBL5850845 | 0.94 | TTR (0.86) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11369713-B2 | Degradable and absorbable hemostatic fiber material, preparation method therefor, and hemostatic fiber article thereof | MEDPRIN REGENERATIVE MEDICAL TECHNOLOGIES CO., LTD. (CN) | 2022-06-28 | — | — | US | disclosed |
| US-20190314543-A1 | DEGRADABLE AND ABSORBABLE HEMOSTATIC FIBER MATERIAL, PREPARATION METHOD THEREFOR, AND HEMOSTATIC FIBER ARTICLE THEREOF | MEDPRIN REGENERATIVE MEDICAL TECHNOLOGIES CO., LTD. (CN) | 2019-10-17 | — | — | US | disclosed |