Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Dioxane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dioxane SCHEMBL2832209 | 1.00 | TTR (0.86) | — | |
| Water SCHEMBL9161357 | 1.00 | TTR (0.86) | — | |
| Water SCHEMBL11426218 | 1.00 | TTR (0.86) | — | |
| Water SCHEMBL1866439 | 1.00 | TTR (0.86) | — | |
| Dioxane SCHEMBL15882140 | 1.00 | TTR (0.86) | — | |
| Dioxane SCHEMBL23090025 | 1.00 | TTR (0.86) | — | |
| Dioxane SCHEMBL5000306 | 0.94 | — | — | |
| Dioxane SCHEMBL21461950 | 0.94 | — | — | |
| Dioxane SCHEMBL27453498 | 0.94 | — | — | |
| Dioxane SCHEMBL6954886 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3085 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119613386-A | Ralset tilobal 1, 4-dioxane solvent compound and preparation method thereof | 杭州科巢生物科技有限公司 | 2025-03-14 | — | — | CN | claimed |
| CN-119409682-A | 1H-indazole compound and preparation method and application thereof | 南京健康产业研究院 | 2025-02-11 | — | — | CN | claimed |
| WO-2025016436-A1 | PREPARATION METHOD FOR KRAS INHIBITOR, INTERMEDIATE THEREOF AND PREPARATION METHOD FOR INTERMEDIATE THEREOF | 上海济煜医药科技有限公司 | 2025-01-23 | — | — | WO | claimed |
| CN-117946018-A | S-triazine LSD1 inhibitor and preparation method and application thereof | 郑州大学 | 2024-04-30 | — | — | CN | claimed |
| CN-117756775-A | Separation method of high-purity anhydrous dioxane | 天津仁爱学院 | 2024-03-26 | — | — | CN | claimed |
| CN-112047907-B | Method for preparing 2, 5-furandimethanol by glucose one-pot method under synergistic catalysis of formic acid hydrogen supply and metal halide | 浙江大学 | 2024-03-19 | — | — | CN | claimed |
| CN-113234049-B | Tyrosinase inhibitor based on grape seed extraction and extraction method and application thereof | 广州纳丽生物科技有限公司 | 2023-12-22 | — | — | CN | claimed |
| CN-116655619-A | 2H-indazole compound and preparation method and application thereof | 南京康立凯医药科技有限公司 | 2023-08-29 | — | — | CN | claimed |
| US-20230192692-A1 | MACROCYCLIC AND CAGE-LIKE MOLECULE BASED ON BIPHEN[n]ARENE AND DERIVATIVE, SYNTHESIS METHOD AND USE THEREOF | TIANJIN NORMAL UNIVERSITY (CN) | 2023-06-22 | — | — | US | claimed |
| CN-115260663-B | Environment-friendly low-odor sealing strip and preparation method thereof | 宁波艾克姆新材料股份有限公司 | 2023-06-16 | — | — | CN | claimed |
| CN-110669496-A | Preparation method of multifunctional fluorescent film | 东北林业大学 | 2020-01-10 | — | — | CN | claimed |
| CN-110615798-A | Preparation method of 6,7-epoxy ligustilide | 四川省中医药科学院 | 2019-12-27 | — | — | CN | claimed |
| US-20190345134-A1 | CRYSTAL FORM OF TIPIFARNIB AND PREPARATION METHOD AND PHARMACEUTICAL COMPOSITION THEREOF | HANGZHOU SOLIPHARMA CO., LTD. (CN) | 2019-11-14 | — | — | US | claimed |
| CN-107619401-B | A kind of preparation method of senkyunolide Ⅰ | 四川省中医药科学院 | 2019-09-20 | — | — | CN | claimed |
| CN-108440494-A | A kind of synthetic method of (S)-N- t-butyl formate -3- amino thiophanes of convenience and high-efficiency | 海南师范大学 | 2018-08-24 | — | — | CN | claimed |
| CN-108084097-A | A kind of method that 5- methyl -2- pyrazine methanol is prepared by dihydroxyacetone (DHA) | 中国科学院大连化学物理研究所 | 2018-05-29 | — | — | CN | claimed |
| CN-106048648-B | The electrochemical catalysis synthetic method of the oxindole class compound of 3- sulfonic groups substitution | 北京工业大学 | 2018-05-25 | — | — | CN | claimed |
| CN-107417686-A | A kind of synthetic method of AVM hereinafter Batan sodium | 北京化工大学 | 2017-12-01 | — | — | CN | claimed |
| CN-105860833-B | A kind of preparation method of alcohol radical aluminium alloy wheel hub coating | 金华格灵功能涂层材料研究所有限公司 | 2017-10-27 | — | — | CN | claimed |
| CN-1275617-A | Method for preparation of repairing porous frame usedd for tissue and organ by a phase separation filter method | UNIV QINGHUA (CN) | 2000-12-06 | — | — | CN | claimed |