Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.65 |
| ▸ | CA2 | P00918 | 3/20 | 0.65 |
| ▸ | CA9 | Q16790 | 3/20 | 0.65 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.65 |
| ▸ | CA1 | P00915 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | GLA | P06280 | 1/20 | 0.65 |
| ▸ | CA3 | P07451 | 1/20 | 0.65 |
| ▸ | CA4 | P22748 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | ACHE | P22303 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL28647331 | 1.00 | CA12 (0.65) | CA12CA2CA9CA14CA1 | |
| Phenol SCHEMBL29200221 | 1.00 | CA12 (0.65) | CA12CA2CA9CA14CA1 | |
| Phenol SCHEMBL6246457 | 0.95 | ALDH1A1 (0.68) | CA12CA2CA9CA14CA1 | |
| Phenol SCHEMBL27847072 | 0.92 | CA12 (0.55) | CA12CA2CA9CA14CA1 | |
| Phenol SCHEMBL2898602 | 0.92 | CA12 (0.55) | CA12CA2CA9CA14CA1 | |
| Phenol SCHEMBL23501812 | 0.90 | ALDH1A1 (0.57) | CA12CA2CA9CA14CA1 | |
| M-Xylene SCHEMBL8740440 | 0.89 | ACHE (0.71) | CA12CA2CA9CA14CA1 | |
| Phenol SCHEMBL27749959 | 0.88 | CA12 (0.50) | CA12CA2CA9CA14CA1 | |
| M-Xylene SCHEMBL28138207 | 0.87 | ACHE (0.68) | CA12CA2CA9CA14CA1 | |
| Toluene SCHEMBL5712879 | 0.85 | ACHE (0.69) | CA12CA2CA9CA14CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111675661-A | Diaryl pyrimidine HIV-1 reverse transcriptase inhibitor containing trans double bond and preparation method and application thereof | 山东大学 | 2020-09-18 | — | — | CN | claimed |
| CN-111675694-A | Oxime group-containing diaryl pyrimidine HIV-1 reverse transcriptase inhibitor and preparation method and application thereof | 山东大学 | 2020-09-18 | — | — | CN | claimed |
| CN-111187222-A | Substituted pyrimidine derivative and preparation method and application thereof | 山东大学 | 2020-05-22 | — | — | CN | claimed |
| CN-106000325-B | A kind of magnetism decoloring material and preparation method thereof | 四川理工学院 | 2019-11-26 | — | — | CN | claimed |
| CN-107778255-B | A kind of Diarylmiazines HIV-1 reverse transcriptase inhibitor and its preparation method and application | 山东大学 | 2019-10-25 | — | — | CN | claimed |
| WO-2019196369-A1 | THIAZOLO-PYRIMIDINE HIV-1 REVERSE TRANSCRIPTASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USES THEREOF | 山东大学 | 2019-10-17 | — | — | WO | claimed |
| WO-2019196370-A1 | FIVE-MEMBERED NON AROMATIC RING-PYRIMIDINE HIV-1 REVERSE TRANSCRIPTASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USES THEREOF | 山东大学 | 2019-10-17 | — | — | WO | claimed |
| CN-107746452-B | Palladium load different-phase catalyst based on micro--mesoporous phenolic resin and preparation method thereof | 大连理工大学 | 2019-10-11 | — | — | CN | claimed |
| CN-110066273-A | A kind of single arylpyrimidines HIV-1 reverse transcriptase inhibitor of the ring containing triazole and the preparation method and application thereof | 山东大学 | 2019-07-30 | — | — | CN | claimed |
| CN-109023322-A | A kind of aqueous epithelium liquid and preparation method thereof instead of phosphating solution | 青岛恒信达化工有限公司 | 2018-12-18 | — | — | CN | claimed |
| CN-106117242-A | Tetrahydric thiapyran miazines derivative and preparation method and application | 山东大学 | 2016-11-16 | — | — | CN | claimed |
| CN-106000325-A | Magnetic decoloration material and preparation method thereof | 四川理工学院 | 2016-10-12 | — | — | CN | claimed |
| CN-105754057-A | P containing phenolic resin polymer and preparation method thereof | 中国科学院大连化学物理研究所 | 2016-07-13 | — | — | CN | claimed |
| CN-105294550-A | 6-substitute diaryl pyridine derivative and preparing method and application thereof | UNIV SHANDONG | 2016-02-03 | — | — | CN | claimed |
| CN-104610525-A | Halogen-free environment-friendly polyurethane oil paint and preparation method thereof | NANJING TONGYUAN NEW MATERIAL TECHNOLOGY CO LTD | 2015-05-13 | — | — | CN | claimed |
| CN-104610794-A | Phosphor-nitrogen intumescent flame retardant, and synthetic method and applications thereof | INST ADVANCED TECHNOLOGY UNIV SCIENCE & TECHNOLOGY CHINA | 2015-05-13 | — | — | CN | claimed |
| CN-104530078-A | Thieno [3, 2-d] pyrimidine derivative and preparation method and application thereof | UNIV SHANDONG | 2015-04-22 | — | — | CN | claimed |
| CN-103450158-B | 2, 4 ,6 - tri-substituted pyrimidine derivative and preparing method and application thereof | UNIV SHANDONG | 2015-04-08 | — | — | CN | claimed |
| CN-103450158-A | 2, 4 ,6 - tri-substituted pyrimidine derivative and preparing method and application thereof | UNIV SHANDONG | 2013-12-18 | — | — | CN | claimed |
| CN-102887887-A | 2-(1-substituted piperidine-4-amino)-6-(substituted phenylamine/phenol) pyridine derivatives and preparation method and application thereof | UNIV SHANDONG | 2013-01-23 | — | — | CN | claimed |