Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18117431 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1CYP2D6CYP2C19MTNR1A | |
| SCHEMBL21462580 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1CYP2D6CYP2C19MTNR1A | |
| SCHEMBL25276694 | 0.89 | ALDH1A1 (0.39) | ALDH1A1TDP1CYP2D6CYP2C19 | |
| SCHEMBL1668685 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TDP1MTNR1AMTNR1BKDM4E | |
| SCHEMBL6249964 | 0.82 | SLC22A6 (0.39) | ALDH1A1TDP1CYP2D6CYP2C19MAPT | |
| SCHEMBL11780257 | 0.81 | GRN (0.37) | ALDH1A1TDP1CYP2D6CYP2C19MTNR1A | |
| SCHEMBL20550825 | 0.78 | CYP2D6 (0.36) | ALDH1A1CYP2D6CYP2C19NPC1RAB9A | |
| SCHEMBL20970384 | 0.76 | CYP2C9 (0.45) | ALDH1A1TDP1SMN1; SMN2LMNAMMP1 | |
| SCHEMBL23445656 | 0.76 | ALDH1A1 (0.56) | ALDH1A1TDP1CYP2D6CYP2C19RAB9A | |
| SCHEMBL20189493 | 0.76 | ATM (0.36) | CYP2D6CYP2C19NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230287003-A1 | BCL6 INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2023-09-14 | — | — | US | disclosed |
| EP-4201939-A1 | BCL6 INHIBITORS | Cancer Research Technology Limited (GB) | 2023-06-28 | — | — | EP | disclosed |
| EP-3774817-B1 | BCL6 INHIBITORS | CANCER RESEARCH TECH LTD (GB) | 2022-12-07 | — | — | EP | disclosed |
| US-20210163497-A1 | BCL6 INHIBITORS | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2021-06-03 | — | — | US | disclosed |
| EP-3774817-A1 | BCL6 INHIBITORS | Cancer Research Technology Limited (GB) | 2021-02-17 | — | — | EP | disclosed |
| WO-2019197842-A1 | BCL6 INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2019-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210163497-A1 | BCL6 INHIBITORS | BCL6, BCL6B, BCL3 | ALDH1A1 2602/4885TDP1 2693/4885CYP2D6 1977/4885 |
| US-20230287003-A1 | BCL6 INHIBITORS | BCL6, BCL6B, BCL3 | ALDH1A1 2602/4885TDP1 2693/4885CYP2D6 1977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.