Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.30 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6249964 | 0.80 | SLC22A6 (0.39) | CYP2D6CYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL21462579 | 0.78 | ALDH1A1 (0.48) | CYP2D6CYP2C19SMN1; SMN2NPC1RAB9A | |
| SCHEMBL21462580 | 0.78 | ALDH1A1 (0.48) | CYP2D6CYP2C19SMN1; SMN2NPC1RAB9A | |
| SCHEMBL18117431 | 0.78 | ALDH1A1 (0.48) | CYP2D6CYP2C19SMN1; SMN2NPC1RAB9A | |
| SCHEMBL17165117 | 0.77 | CYP2D6 (0.33) | CYP2D6CYP2C19 | |
| SCHEMBL12164763 | 0.74 | TSHR (0.40) | CYP2D6CYP2C19RAB9AALDH1A1MMP1 | |
| SCHEMBL11780257 | 0.74 | GRN (0.37) | CYP2D6CYP2C19SMN1; SMN2NPC1RAB9A | |
| SCHEMBL20189493 | 0.74 | ATM (0.36) | CYP2D6CYP2C19NPC1RAB9AMMP2 | |
| SCHEMBL25276694 | 0.74 | ALDH1A1 (0.39) | CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL28709191 | 0.74 | CYP2D6 (0.42) | CYP2D6CYP2C19NPC1RAB9AFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180318438-A1 | ANTIBODY DRUG CONJUGATES OF KINESIN SPINDEL PROTEIN (KSP) INHIBITORS WITH ANTI-TWEAKR-ANTIBODIES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180318438-A1 | ANTIBODY DRUG CONJUGATES OF KINESIN SPINDEL PROTEIN (KSP) INHIBITORS WITH ANTI-TWEAKR-ANTIBODIES | KIF5B, KIF23, KIF2C | CYP2D6 4773/4885CYP2C19 4878/4885PKM 1204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.