SCHEMBL21462986

SCHEMBL21462986

OCCOc1ccc(-c2ccc(-c3ccccc3)c3c2Cc2cccc(-c4ccccc4)c2-3)cc1-c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A9 P48067 8/20 0.43
ALOX5AP P20292 2/20 0.39
FEN1 P39748 2/20 0.39
AR P10275 1/20 0.39
LMNA P02545 3/20 0.38
HTT P42858 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
HTR7 P34969 1/20 0.37
POLB P06746 1/20 0.37
RARA P10276 1/20 0.37
RARB P10826 1/20 0.37
RARG P13631 1/20 0.37
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TP53 P04637 1/20 0.36
MAPK1 P28482 1/20 0.36
RAB9A P51151 1/20 0.36
THRA P10827 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28438046 0.87 LMNA (0.40) SLC6A9LMNAHTTMEN1KMT2A
SCHEMBL577450 0.86 SLC6A9 (0.45) SLC6A9ALOX5APFEN1ARLMNA
SCHEMBL29216759 0.82 SLC6A9 (0.44) SLC6A9ARLMNAHTTMEN1
SCHEMBL28747598 0.77 LMNA (0.43) LMNAHTTMEN1KMT2AHTR7
SCHEMBL30366251 0.76 IDO1 (0.39) SLC6A9ALOX5APFEN1ARLMNA
SCHEMBL21880030 0.76 SLC6A9 (0.50) SLC6A9ARLMNAHTTRARA
SCHEMBL21227064 0.75 IDO1 (0.44) SLC6A9MEN1KMT2AKDM4EALDH1A1
SCHEMBL30367750 0.75 LMNA (0.41) SLC6A9ALOX5APFEN1ARLMNA
SCHEMBL21880029 0.74 SLC6A9 (0.48) SLC6A9ARLMNAHTTMEN1
SCHEMBL22418844 0.74 ESR2 (0.49)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111465589-B Compound having fluorene skeleton and method for producing same 帝人株式会社 2024-01-05 CN disclosed
CN-111527125-B Poly (ester) carbonate and method for producing poly (ester) carbonate 帝人株式会社 2022-07-22 CN disclosed
WO-2020184113-A1 ORGANIC-INORGANIC COMPOSITE MATERIAL 帝人株式会社 2020-09-17 WO disclosed
CN-111527125-A Poly (ester) carbonate and method for producing poly (ester) carbonate 帝人株式会社 2020-08-11 CN disclosed
CN-111465589-A Compound having fluorene skeleton and method for producing same 帝人株式会社 2020-07-28 CN disclosed
CN-110741030-A Thermoplastic resin and optical member 帝人株式会社 2020-01-31 CN disclosed
WO-2019198677-A1 PHOSPHORUS-CONTAINING THERMOPLASTIC RESIN, FLAME-RETARDANT RESIN COMPOSITION AND MOLDED ARTICLE 帝人株式会社 2019-10-17 WO disclosed