Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.46 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.46 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMAD3 | P84022 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2145809 | 0.99 | SMN1; SMN2 (0.56) | SMN1; SMN2MEN1KMT2AL3MBTL1TSHR | |
| Hydrochloric Acid SCHEMBL2145807 | 0.99 | SMN1; SMN2 (0.56) | SMN1; SMN2MEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL30587419 | 0.92 | SMN1; SMN2 (0.54) | SMN1; SMN2MEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL2146242 | 0.92 | ALOX15 (0.49) | SMN1; SMN2MEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL13745503 | 0.92 | SMN1; SMN2 (0.64) | SMN1; SMN2MEN1KMT2AL3MBTL1TSHR | |
| Hydrochloric Acid SCHEMBL2146418 | 0.90 | ALOX15 (0.48) | SMN1; SMN2MEN1KMT2AL3MBTL1TSHR | |
| Hydrochloric Acid SCHEMBL2146412 | 0.90 | ALOX15 (0.48) | SMN1; SMN2MEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL2146920 | 0.90 | ALOX15 (0.50) | SMN1; SMN2MEN1KMT2AL3MBTL1TSHR | |
| Hydrochloric Acid SCHEMBL2145957 | 0.89 | ALOX15 (0.49) | SMN1; SMN2MEN1KMT2AL3MBTL1TSHR | |
| Hydrochloric Acid SCHEMBL2145967 | 0.89 | ALOX15 (0.49) | SMN1; SMN2MEN1KMT2AL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011088045-A1 | AURORA KINASE COMPOUNDS AND METHODS OF THEIR USE | AMBIT BIOSCIENCES CORPORATION (US) | 2011-07-21 | — | — | WO | disclosed |