Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.55 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.55 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2146376 | 0.92 | SMN1; SMN2 (0.57) | SMN1; SMN2MEN1KMT2AL3MBTL1GNAI3 | |
| SCHEMBL19010582 | 0.91 | ALOX15 (0.54) | SMN1; SMN2MEN1KMT2AL3MBTL1GNAI3 | |
| Hydrochloric Acid SCHEMBL2145807 | 0.90 | SMN1; SMN2 (0.56) | SMN1; SMN2MEN1KMT2AL3MBTL1GNAI3 | |
| Hydrochloric Acid SCHEMBL2145809 | 0.90 | SMN1; SMN2 (0.56) | SMN1; SMN2MEN1KMT2AL3MBTL1GNAI3 | |
| SCHEMBL16908301 | 0.89 | ALOX15 (0.56) | SMN1; SMN2GNAI3GNAO1GNAI1TSHR | |
| SCHEMBL13875530 | 0.89 | SMN1; SMN2 (0.72) | SMN1; SMN2MEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL14761461 | 0.88 | SMN1; SMN2 (0.56) | SMN1; SMN2MEN1KMT2AL3MBTL1GNAI3 | |
| SCHEMBL19849351 | 0.88 | SMN1; SMN2 (0.70) | SMN1; SMN2MEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL3021250 | 0.86 | LMNA (0.56) | SMN1; SMN2MEN1KMT2AGNAI3GNAO1 | |
| SCHEMBL14761832 | 0.84 | DRD2 (0.57) | SMN1; SMN2MEN1KMT2AL3MBTL1GNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009098282-A1 | LOW MOLECULAR WEIGHT 2,5-DISUBSTITUTED THIOPHENE DERIVATIVES AND USE THEREOF IN THERAPY | NOVASAID AB (SE) | 2009-08-13 | — | — | WO | disclosed |