Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | MLNR | O43193 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9697641 | 0.89 | LTA4H (0.39) | LTA4HGAASMPD1FDPSPPARG | |
| SCHEMBL27305356 | 0.89 | LTA4H (0.39) | LTA4HGAASMPD1FDPSPPARG | |
| SCHEMBL11698195 | 0.88 | GAA (0.40) | LTA4HGAAFDPSPPARGALDH1A1 | |
| SCHEMBL17201874 | 0.84 | LTA4H (0.43) | LTA4HGAAFDPSPPARGPPARA | |
| SCHEMBL2391802 | 0.84 | PPARG (0.44) | LTA4HGAAFDPSPPARGPPARA | |
| SCHEMBL9453368 | 0.84 | PPARG (0.44) | LTA4HGAAFDPSPPARGPPARA | |
| SCHEMBL11065588 | 0.84 | PPARG (0.44) | LTA4HGAAFDPSPPARGPPARA | |
| SCHEMBL1527669 | 0.84 | PPARG (0.44) | LTA4HGAAFDPSPPARGPPARA | |
| SCHEMBL21991 | 0.82 | PPARG (0.43) | LTA4HGAAPPARGPPARACNR1 | |
| SCHEMBL28552515 | 0.82 | PPARG (0.43) | LTA4HGAAPPARGPPARACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12187662-B2 | FOXM1 inhibitor compositions and methods of using the same | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2025-01-07 | — | — | US | disclosed |
| EP-3774708-A1 | FOXM1 INHIBITOR COMPOSITIONS AND METHODS OF USING THE SAME | The Board of Trustees of the University of Illinois (US) | 2021-02-17 | — | — | EP | disclosed |
| US-20210032193-A1 | FOXM1 INHIBITOR COMPOSITIONS AND METHODS OF USING THE SAME | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2021-02-04 | — | — | US | disclosed |
| CN-112218845-A | FOXM1 inhibitor compositions and methods of use thereof | 伊利诺伊大学理事会 | 2021-01-12 | — | — | CN | disclosed |
| WO-2019199863-A1 | FOXM1 INHIBITOR COMPOSITIONS AND METHODS OF USING THE SAME | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2019-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210032193-A1 | FOXM1 INHIBITOR COMPOSITIONS AND METHODS OF USING THE SAME | FOXM1, FOXO1, TP53 | LTA4H 4562/4885GAA 3970/4885SMPD1 4480/4885 |
| US-12187662-B2 | FOXM1 inhibitor compositions and methods of using the same | FOXM1, FOXO1, TP53 | LTA4H 4562/4885GAA 3970/4885SMPD1 4480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.