Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.88 |
| ▸ | METAP2 | P50579 | 3/20 | 0.88 |
| ▸ | MMP2 | P08253 | 2/20 | 0.88 |
| ▸ | METAP1 | P53582 | 2/20 | 0.88 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.88 |
| ▸ | COMT | P21964 | 1/20 | 0.88 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.88 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.88 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.72 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.72 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxyquinoline SCHEMBL5068192 | 0.94 | TSHR (0.91) | TSHRMETAP2MMP2METAP1CHRM1 | |
| Oxyquinoline SCHEMBL29365411 | 0.94 | TSHR (1.00) | TSHRMETAP2MMP2METAP1CHRM1 | |
| Oxyquinoline SCHEMBL37189 | 0.94 | TSHR (1.00) | TSHRMETAP2MMP2METAP1CHRM1 | |
| Oxyquinoline SCHEMBL29716519 | 0.94 | TSHR (1.00) | TSHRMETAP2MMP2METAP1CHRM1 | |
| Oxyquinoline SCHEMBL253313 | 0.94 | TSHR (1.00) | TSHRMETAP2MMP2METAP1CHRM1 | |
| Oxyquinoline SCHEMBL2590173 | 0.92 | TSHR (0.88) | TSHRMETAP2MMP2METAP1CHRM1 | |
| Oxyquinoline SCHEMBL4396353 | 0.92 | TSHR (0.88) | TSHRMETAP2MMP2METAP1CHRM1 | |
| Oxyquinoline SCHEMBL10415862 | 0.92 | TSHR (0.88) | TSHRMETAP2MMP2METAP1CHRM1 | |
| Oxyquinoline SCHEMBL8969561 | 0.92 | TSHR (0.88) | TSHRMETAP2MMP2METAP1CHRM1 | |
| Oxyquinoline SCHEMBL23522696 | 0.91 | TSHR (0.95) | TSHRMETAP2MMP2METAP1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019199879-A1 | HYDROPHOBIC COATINGS AND METHODS OF MAKING HYDROPHOBIC AND OLEOPHOBIC COATINGS USING ATOMIC OR MOLECULAR DEPOSITION | ALD NANOSOLUTIONS, INC. (US) | 2019-10-17 | — | — | WO | disclosed |