SCHEMBL537504

SCHEMBL537504

N#CC(CC(=O)O)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
SLC22A6 Q4U2R8 1/20 0.39
FOLH1 Q04609 2/20 0.36
GABRR1 P24046 2/20 0.33
LMNA P02545 1/20 0.33
OR51E2 Q9H255 1/20 0.32
TSHR P16473 1/20 0.32
CPA1 P15085 2/20 0.30
CPB1 P15086 1/20 0.30
CPA3 P15088 1/20 0.30
CPB2 Q96IY4 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propene SCHEMBL4543717 0.87 TDP1 (0.34) TDP1SMN1; SMN2SLC22A6
SCHEMBL11628782 0.80 MCL1 (0.39)
SCHEMBL28155378 0.80 ALDH1A1 (0.40) TDP1
SCHEMBL21848010 0.78 SLC22A6 (0.35) TDP1SMN1; SMN2SLC22A6GABRR1LMNA
SCHEMBL11693375 0.78 SLC1A3 (0.31)
SCHEMBL1305300 0.78 SLC1A2 (0.35) OR51E2
SCHEMBL15263375 0.76
SCHEMBL22401640 0.75 TET2 (0.46) FOLH1LMNAMAPT
SCHEMBL14192720 0.75 KMT2A (0.34) TDP1SMN1; SMN2SLC22A6TSHR
SCHEMBL5150036 0.74 TDP1 (0.43) TDP1SMN1; SMN2SLC22A6FOLH1GABRR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024088244-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, PREPARATION METHOD THEREFOR AND USE THEREOF 中国石油化工股份有限公司 2024-05-02 WO claimed
CN-107344978-B Catalyst component for olefin polymerization, catalyst system and application thereof 中国石油化工股份有限公司 2020-06-09 CN claimed
US-8541333-B2 Catalyst component for olefin polymerization and a catalyst comprising the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2013-09-24 US claimed
EP-2287208-B1 A catalyst component for olefin polymerization and a catalyst comprising the same CHINA PETROLEUM & CHEMICAL (CN) 2012-05-09 EP claimed
EP-2287208-A1 A catalyst component for olefin polymerization and a catalyst comprising the same China Petroleum & Chemical Corporation (CN) 2011-02-23 EP claimed
US-20110040051-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND A CATALYST COMPRISING THE SAME BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2011-02-17 US claimed
JP-62267268-A None JP disclosed
CN-119930888-A Ethylene-propylene binary copolymer with wide molecular weight distribution and high melt strength, and preparation method and application thereof 中国石油化工股份有限公司 2025-05-06 CN disclosed
CN-119930870-A Catalyst system for preparing polypropylene with wide molecular weight distribution and high melt strength and application thereof 中国石油化工股份有限公司 2025-05-06 CN disclosed
CN-119930887-A Terpolymer with wide molecular weight distribution and high melt strength as well as preparation method and application thereof 中国石油化工股份有限公司 2025-05-06 CN disclosed
CN-119930889-A Ethylene-propylene binary copolymer with high melt strength and preparation method and application thereof 中国石油化工股份有限公司 2025-05-06 CN disclosed
CN-119930890-A Terpolymer with high melt strength and preparation method and application thereof 中国石油化工股份有限公司 2025-05-06 CN disclosed
CN-119930865-A Catalyst system for preparing high melt strength polypropylene and application thereof 中国石油化工股份有限公司 2025-05-06 CN disclosed
US-20070141684-A1 Preparation of gamma-amino acids having affinity for the alpha-2-delta protein PFIZER INC 2007-06-21 US disclosed
EP-1767528-A1 PROCESS FOR PRODUCING 5-HYDROXY-4-THIOMETHYLPYRAZOLE COMPOUND IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) 2007-03-28 EP disclosed
JP-2004269473-A METHOD FOR PRODUCING NITRILE DERIVATIVE TORAY IND INC 2004-09-30 JP disclosed
JP-S62267268-A PRODUCTION OF PYRAZOLONE DERIVATIVE MITSUBISHI CHEM IND LTD 1987-11-19 JP disclosed
US-4521344-A Cyano-dicarboxylate MONSANTO COMPANY (US) 1985-06-04 US disclosed
US-4514340-A Cyano-polycarboxylates MONSANTO COMPANY (US) 1985-04-30 US disclosed
US-4442298-A Chemical synthesis of ethylene/maleic anhydride dimer with phenylethyl end group MONSANTO COMPANY (US) 1984-04-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070141684-A1 Preparation of gamma-amino acids having affinity for the alpha-2-delta protein SCN2A, CACNG2, SCN1A TDP1 4202/4885SMN1; SMN2 2340/4885SLC22A6 2282/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.