Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 5/20 | 0.58 |
| ▸ | SRC | P12931 | 5/20 | 0.58 |
| ▸ | KDR | P35968 | 5/20 | 0.58 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.58 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.58 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.58 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.58 |
| ▸ | PRKDC | P78527 | 5/20 | 0.58 |
| ▸ | EGFR | P00533 | 4/20 | 0.58 |
| ▸ | HCK | P08631 | 4/20 | 0.58 |
| ▸ | MTOR | P42345 | 4/20 | 0.58 |
| ▸ | EPHB4 | P54760 | 4/20 | 0.58 |
| ▸ | FGFR1 | P11362 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31367061 | 1.00 | ABL1 (0.58) | ABL1SRCKDRPIK3CDPIK3CA | |
| SCHEMBL2237756 | 0.86 | FGFR1 (0.50) | ABL1SRCKDRPIK3CDPIK3CA | |
| SCHEMBL12347206 | 0.83 | PIK3CD (0.48) | ABL1SRCKDRPIK3CDPIK3CA | |
| SCHEMBL23917483 | 0.82 | PIK3CD (0.60) | ABL1SRCKDRPIK3CDPIK3CA | |
| SCHEMBL3605078 | 0.80 | PIK3CD (0.61) | ABL1SRCKDRPIK3CDPIK3CA | |
| SCHEMBL20748491 | 0.77 | PIK3CG (0.54) | ABL1SRCKDRPIK3CDPIK3CA | |
| SCHEMBL12162 | 0.77 | PIK3CD (0.74) | ABL1SRCKDRPIK3CDPIK3CA | |
| SCHEMBL19414290 | 0.75 | SRC (0.57) | ABL1SRCKDRPIK3CDPIK3CA | |
| SCHEMBL17970655 | 0.75 | KDR (0.51) | ABL1SRCKDRPIK3CDPIK3CA | |
| SCHEMBL30387175 | 0.75 | PIK3CD (0.55) | ABL1SRCKDRPIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11858907-B2 | Kinase modulators | RHIZEN PHARMACEUTICALS AG (CH) | 2024-01-02 | — | — | US | disclosed |
| US-10442783-B2 | 2,3-disubstituted chromen-4-one compounds as modulators of protein kinases | RHIZEN PHARMACEUTICALS SA (CH) | 2019-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10442783-B2 | 2,3-disubstituted chromen-4-one compounds as modulators of protein kinases | PIK3CB, PIK3CD, PDPK1 | ABL1 329/4885SRC 202/4885KDR 866/4885 |
| US-11858907-B2 | Kinase modulators | RPS6KA1, RPS6KA2, PRKAR2A | ABL1 258/4885SRC 110/4885KDR 823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.