Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 5/20 | 0.58 |
| ▸ | SRC | P12931 | 5/20 | 0.58 |
| ▸ | KDR | P35968 | 5/20 | 0.58 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.58 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.58 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.58 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.58 |
| ▸ | PRKDC | P78527 | 5/20 | 0.58 |
| ▸ | EGFR | P00533 | 4/20 | 0.58 |
| ▸ | HCK | P08631 | 4/20 | 0.58 |
| ▸ | MTOR | P42345 | 4/20 | 0.58 |
| ▸ | EPHB4 | P54760 | 4/20 | 0.58 |
| ▸ | FGFR1 | P11362 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21467059 | 1.00 | ABL1 (0.58) | ABL1SRCKDRPIK3CDPIK3CA | |
| SCHEMBL2237756 | 0.86 | FGFR1 (0.50) | ABL1SRCKDRPIK3CDPIK3CA | |
| SCHEMBL12347206 | 0.83 | PIK3CD (0.48) | ABL1SRCKDRPIK3CDPIK3CA | |
| SCHEMBL23917483 | 0.82 | PIK3CD (0.60) | ABL1SRCKDRPIK3CDPIK3CA | |
| SCHEMBL3605078 | 0.80 | PIK3CD (0.61) | ABL1SRCKDRPIK3CDPIK3CA | |
| SCHEMBL20748491 | 0.77 | PIK3CG (0.54) | ABL1SRCKDRPIK3CDPIK3CA | |
| SCHEMBL12162 | 0.77 | PIK3CD (0.74) | ABL1SRCKDRPIK3CDPIK3CA | |
| SCHEMBL19414290 | 0.75 | SRC (0.57) | ABL1SRCKDRPIK3CDPIK3CA | |
| SCHEMBL17970655 | 0.75 | KDR (0.51) | ABL1SRCKDRPIK3CDPIK3CA | |
| SCHEMBL30387175 | 0.75 | PIK3CD (0.55) | ABL1SRCKDRPIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3888657-B1 | HETEROCYCLYLAMINES AS PI3K INHIBITORS | INCYTE HOLDINGS CORP (US) | 2025-03-19 | — | — | EP | disclosed |