Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 15/20 | 0.51 |
| ▸ | NPC1 | O15118 | 12/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.49 |
| ▸ | TP53 | P04637 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 6/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 6/20 | 0.49 |
| ▸ | RELA | Q04206 | 6/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21499387 | 0.87 | PLAU (0.43) | RAB9ANPC1GAASMN1; SMN2TP53 | |
| SCHEMBL21468514 | 0.73 | AURKA (0.62) | RAB9ANPC1GAASMN1; SMN2TP53 | |
| SCHEMBL1719610 | 0.70 | MAPT (0.67) | SMN1; SMN2TP53MAPTALDH1A1HPGD | |
| SCHEMBL21468516 | 0.70 | NPC1 (0.68) | RAB9ANPC1GAASMN1; SMN2TP53 | |
| SCHEMBL950878 | 0.69 | ALDH1A1 (0.46) | RAB9ANPC1GAASMN1; SMN2MAPT | |
| SCHEMBL1719345 | 0.69 | MAPT (0.63) | RAB9AGAASMN1; SMN2TP53MAPT | |
| SCHEMBL2244056 | 0.68 | BAZ2B (0.67) | RAB9ANPC1GAASMN1; SMN2TP53 | |
| SCHEMBL950506 | 0.67 | NPC1 (0.38) | RAB9ANPC1MAPTHTTALDH1A1 | |
| SCHEMBL2245582 | 0.66 | BAZ2B (0.64) | RAB9ANPC1GAASMN1; SMN2TP53 | |
| SCHEMBL21499347 | 0.66 | DHODH (0.56) | RAB9ANPC1SMN1; SMN2TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10450263-B2 | Benzo annulenes as antiviral agents | SOUTHERN RESEARCH INSTITUTE (US) | 2019-10-22 | — | — | US | disclosed |
| US-10450263-B2 | Benzo annulenes as antiviral agents | SOUTHERN RESEARCH INSTITUTE (US) | 2019-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10450263-B2 | Benzo annulenes as antiviral agents | MAVS, ZC3HAV1, GABBR1 | RAB9A 1314/4885NPC1 908/4885GAA 186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.