SCHEMBL2146990

SCHEMBL2146990

CCO[Si](OCC)(OCC)OC(CC)OCC1CO1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL305201 0.85 ALDH1A1 (0.35) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL3455337 0.80 SMN1; SMN2 (0.43) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL3993994 0.79 ALDH1A1 (0.38) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL6902061 0.78 ALDH1A1 (0.37) ALDH1A1SMN1; SMN2
SCHEMBL27997114 0.78 SMN1; SMN2 (0.39) ALDH1A1SMN1; SMN2TDP1TSHR
SCHEMBL28881398 0.76 TSHR (0.42) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL3856312 0.74 SMN1; SMN2 (0.42) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL7633176 0.73 ALDH1A1 (0.34) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL30969973 0.73 SMN1; SMN2 (0.33) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL8207723 0.73 ALDH1A1 (0.39) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2523916-B1 COMPOSITE MATERIAL AND METHOD FOR THE PRODUCTION THEREOF SCHOTT AG (DE) 2017-08-23 EP disclosed
EP-2523917-A1 METHOD FOR PRODUCING A DISK WITH A STRUCTURED SURFACE, AND DISK WITH A STRUCTURED SURFACE Schott AG (DE) 2012-11-21 EP disclosed
EP-2523915-A1 GLASS OR GLASS-CERAMIC COMPOSITE MATERIAL, AND METHOD FOR THE PRODUCTION THEREOF Schott AG (DE) 2012-11-21 EP disclosed
EP-2523916-A1 COMPOSITE MATERIAL AND METHOD FOR THE PRODUCTION THEREOF Schott AG (DE) 2012-11-21 EP disclosed
WO-2011085996-A1 COMPOSITE MATERIAL AND METHOD FOR THE PRODUCTION THEREOF SCHOTT AG (DE) 2011-07-21 WO disclosed
WO-2011085995-A1 GLASS OR GLASS-CERAMIC COMPOSITE MATERIAL, AND METHOD FOR THE PRODUCTION THEREOF SCHOTT AG (DE) 2011-07-21 WO disclosed
WO-2011085997-A1 METHOD FOR PRODUCING A DISK WITH A STRUCTURED SURFACE, AND DISK WITH A STRUCTURED SURFACE SCHOTT AG (DE) 2011-07-21 WO disclosed