SCHEMBL305201

SCHEMBL305201

CCC(OCC1CO1)O[Si](OC)(OC)OC

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
TSHR P16473 2/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28350586 0.87 ALDH1A1 (0.36) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL2146990 0.85 ALDH1A1 (0.34) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL3455337 0.81 SMN1; SMN2 (0.43) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL3993994 0.81 ALDH1A1 (0.38) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL6902061 0.80 ALDH1A1 (0.37) ALDH1A1SMN1; SMN2
SCHEMBL28881398 0.77 TSHR (0.42) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL29150942 0.76 ALDH1A1 (0.33) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL27997114 0.76 SMN1; SMN2 (0.39) ALDH1A1SMN1; SMN2TDP1TSHR
SCHEMBL8207723 0.74 ALDH1A1 (0.39) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL8158638 0.73 THRB (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106413874-B Method for preparing silica-carbon allotrope composite material and using method thereof LES创新材料公司 2020-05-15 CN disclosed
US-20120115748-A1 METHODS FOR MAKING AND USING SPR MICROARRAYS PLEXERA LLC (US) 2012-05-10 US disclosed
US-8094315-B2 Methods for making and using SPR microarrays PLEXERA LLC (US) 2012-01-10 US disclosed
US-20090093067-A1 METHODS FOR MAKING AND USING SPR MICROARRAYS LUMERA CORPORATION (US) 2009-04-09 US disclosed
US-7463358-B2 Highly stable surface plasmon resonance plates, microarrays, and methods LUMERA CORPORATION (US) 2008-12-09 US disclosed
US-20070128455-A1 Highly stable surface plasmon resonance plates, microarrays, and methods SUZHOU PUXIN LIFE SCIENCE & TECHNOLOGY., LTD. (CN) 2007-06-07 US disclosed
US-20010011117-A1 ADDITION CROSSLINKING SILICONE RUBBER MIXTURES, A PROCESS FOR THE PREPARATION THEREOF, A PROCESS FOR THE PREPARATION OF COMPOSITE MOLDED PARTS AND THE USE THEREOF MOMENTIVE PERFORMANCE MATERIALS INC. 2001-08-02 US disclosed