Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 16/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23327015 | 0.86 | HDAC8 (0.38) | HDAC8PTPN1 | |
| SCHEMBL21470447 | 0.81 | ACACB (0.34) | — | |
| SCHEMBL23326809 | 0.76 | MET (0.33) | — | |
| SCHEMBL21470423 | 0.74 | ESR2 (0.41) | — | |
| SCHEMBL21593114 | 0.73 | NR1H2 (0.44) | HDAC8 | |
| SCHEMBL21470766 | 0.73 | HTR6 (0.39) | HDAC8 | |
| SCHEMBL23326766 | 0.72 | NR1H2 (0.47) | — | |
| SCHEMBL18435172 | 0.69 | PTPN1 (0.47) | HDAC8PTPN1 | |
| SCHEMBL23762243 | 0.68 | NR1H2 (0.42) | — | |
| SCHEMBL23353521 | 0.68 | MET (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019200120-A1 | DIHYDROISOQUINOLINE-2(1H)-CARBOXAMIDE AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | LYCERA CORPORATION (US) | 2019-10-17 | — | — | WO | disclosed |