⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24454146 | 0.82 | — | — | |
| SCHEMBL24503351 | 0.77 | — | — | |
| SCHEMBL17919400 | 0.73 | — | — | |
| SCHEMBL21515204 | 0.73 | — | — | |
| SCHEMBL22872320 | 0.73 | — | — | |
| SCHEMBL22096299 | 0.72 | — | — | |
| SCHEMBL18806874 | 0.72 | — | — | |
| SCHEMBL26818797 | 0.70 | TDP1 (0.35) | — | |
| SCHEMBL21534069 | 0.70 | SLC6A3 (0.34) | — | |
| SCHEMBL1904763 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11793880-B2 | Conjugates of quaternized tubulysin compounds | SEAGEN INC. (US) | 2023-10-24 | — | — | US | disclosed |
| US-11638762-B2 | Targeted delivery of nicotinamide adenine dinucleotide salvage pathway inhibitors | SEAGEN INC. (US) | 2023-05-02 | — | — | US | disclosed |
| US-11116847-B2 | Methylene carbamate linkers for use with targeted-drug conjugates | SEAGEN INC. (US) | 2021-09-14 | — | — | US | disclosed |
| US-20190314519-A1 | TARGETED DELIVERY OF NICOTINAMIDE ADENINE DINUCLEOTIDE SALVAGE PATHWAY INHIBITORS | SEATTLE GENETICS, INC. (US) | 2019-10-17 | — | — | US | disclosed |