Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.32 |
| ▸ | CHRNA1 | P02708 | 4/20 | 0.32 |
| ▸ | CHRNG | P07510 | 4/20 | 0.32 |
| ▸ | CHRNB1 | P11230 | 4/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.32 |
| ▸ | CHRND | Q07001 | 4/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.31 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18806874 | 0.76 | — | — | |
| SCHEMBL23080188 | 0.75 | — | — | |
| SCHEMBL11207053 | 0.72 | SLC6A3 (0.33) | SLC6A3SLC6A2CHRNA1CHRNGCHRNB1 | |
| SCHEMBL21471172 | 0.70 | — | — | |
| SCHEMBL18594704 | 0.69 | — | — | |
| SCHEMBL980416 | 0.69 | SLC6A3 (0.39) | SLC6A3SLC6A2CHRNA1CHRNGCHRNB1 | |
| SCHEMBL18653492 | 0.68 | SLC6A3 (0.42) | SLC6A3SLC6A2CHRNA1CHRNGCHRNB1 | |
| SCHEMBL14010448 | 0.68 | SLC6A3 (0.42) | SLC6A3SLC6A2CHRNA1CHRNGCHRNB1 | |
| SCHEMBL14601332 | 0.68 | SLC6A3 (0.42) | SLC6A3SLC6A2CHRNA1CHRNGCHRNB1 | |
| SCHEMBL1904763 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022266753-A1 | BIVALENT COMPOUNDS, CONJUGATES AND USES THEREOF | Risen (Suzhou) Pharma Tech Co., Ltd. (CN) | 2022-12-29 | — | — | WO | disclosed |
| US-20190328893-A1 | Conjugates And Conjugating Reagents Comprising A Linker That Includes At Least Two (-CH2-CH2-0-) Units In A Ring | POLYTHERICS LIMITED (GB) | 2019-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190328893-A1 | Conjugates And Conjugating Reagents Comprising A Linker That Includes At Least Two (-CH2-CH2-0-) Units In A Ring | BCR, CD2BP2, LANCL1 | SLC6A3 4786/4885SLC6A2 4446/4885CHRNA1 3260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.